Introduction The 18-kDa translocator protein (TSPO) is increasingly recognized as a
molecular target for PET imaging of inflammatory responses in various central nervous …

Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Major depression represents a complex and prevalent psychological disease that is
characterized by persistent depressed mood, impaired cognitive function and complicated …

Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …

Background Persistent inflammation dysregulation and cognitive decline have been
associated with several trauma-and stress-related disorders such as posttraumatic stress …

Multimorbidity and depression are complex multifactorial conditions with major implications
for older individuals, their families, and healthcare providers. In this scoping review, we …

Nowadays depression is considered as a systemic illness with different biological
mechanisms involved in its etiology, including inflammatory response, hypothalamic …

Astrocyte-derived extracellular vesicles (ADEs) allow the in vivo probing of the inflammatory
status of astrocytes practical. Serum sample and ADEs were used to test the inflammatory …

It is widely held that schizophrenia involves an active process of peripheral inflammation that
induces or reflects brain inflammation with activation of microglia, the brain's resident …

Mitochondria are regarded as the metabolic centers of cells and are integral in many other
cell processes, including the immune response. Each mitochondrion contains numerous …