Pediatric lupus—are there differences in presentation, genetics, response to therapy, and damage accrual compared with adult lupus?

R Mina, HI Brunner - Rheumatic Disease Clinics, 2010 - rheumatic.theclinics.com
An estimated 10% to 20% of patients experience the onset of systemic lupus erythematosus
(SLE) before adulthood. More precise estimates are difficult due to a lack of a clear age limit …

B-lymphocyte lineage cells and the respiratory system

A Kato, KE Hulse, BK Tan, RP Schleimer - Journal of allergy and clinical …, 2013 - Elsevier
Adaptive humoral immune responses in the airways are mediated by B cells and plasma
cells that express highly evolved and specific receptors and produce immunoglobulins of …

Cardiovascular and pulmonary manifestations of systemic lupus erythematosus

K Tselios, MB Urowitz - Current rheumatology reviews, 2017 - ingentaconnect.com
Background: Systemic lupus erythematosus (SLE) is characterized by various clinical
manifestations and immunologic abnormalities. Cardiovascular and respiratory system …

Systemic lupus erythematosus and lung involvement: a comprehensive review

JI Shin, KH Lee, S Park, JW Yang, HJ Kim… - Journal of Clinical …, 2022 - mdpi.com
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multiorgan
manifestations, including pleuropulmonary involvement (20–90%). The precise mechanism …

Glycosaminoglycan (GAG) biosynthesis and GAG-binding proteins

L Zhang - Progress in molecular biology and translational …, 2010 - Elsevier
Two major types of glycosaminoglycan (GAG) polysaccharides, heparan sulfate and
chondroitin sulfate, are polymerized and modified by enzymes that are encoded by more …

Lung disease related to collagen vascular disease

DA Lynch - Journal of thoracic imaging, 2009 - journals.lww.com
Collagen vascular disease is one of the most common causes of chronic infiltrative lung
disease. Patterns of lung injury from collagen vascular disease include nonspecific …

Pulmonary manifestations of systemic lupus erythematosus

S Mittoo, CD Fell - Seminars in respiratory and critical care …, 2014 - thieme-connect.com
Systemic lupus erythematosus (SLE) is a systemic inflammatory disease, characterized
serologically by an autoantibody response to nucleic antigens, and clinically by injury and/or …

Pleural and pulmonary involvement in systemic lupus erythematosus

O Torre, S Harari - La Presse Médicale, 2011 - Elsevier
Systemic lupus erythematosus (SLE) is a rare complex autoimmune disease with a
multisystem involvement. The clinical manifestations of this disease include an …

Diffuse pulmonary hemorrhage: clues to the diagnosis

JP Lichtenberger III, SR Digumarthy, GF Abbott… - Current problems in …, 2014 - Elsevier
Diffuse pulmonary hemorrhage (DPH) refers to an uncommon but significant condition of
bleeding into the alveolar space. Anemia and hemoptysis are important clinical features, but …

Systemic lupus erythematosus and thrombosis

M Bazzan, A Vaccarino, F Marletto - Thrombosis journal, 2015 - Springer
Abstract Systemic Lupus Erythematosus (SLE) is an acquired, multiorgan, autoimmune
disease. Clinical presentation is extremely variable and heterogeneous. It has been shown …