Learning from nature: Bioinspired chlorin-based photosensitizers immobilized on carbon materials for combined photodynamic and photothermal therapy

LD Dias, IS Mfouo-Tynga - Biomimetics, 2020 - mdpi.com
Chlorophylls, which are chlorin-type photosensitizers, are known as the key building blocks
of nature and are fundamental for solar energy metabolism during the photosynthesis …

Aggregation‐induced emission luminogens for mitochondria‐targeted cancer therapy

Y Huang, G Zhang, R Zhao, D Zhang - ChemMedChem, 2020 - Wiley Online Library
The importance of mitochondria in tumorigenesis makes these organelles an ideal target for
cancer therapy. In recent years, luminogens with the aggregation‐induced emission (AIE) …

Macrocycles and supramolecules as antioxidants: Excellent scaffolds for development of potential therapeutic agents

JS Lee, I Song, PB Shinde, SB Nimse - Antioxidants, 2020 - mdpi.com
Oxidative stress due to the high levels of reactive oxygen species (ROS) that damage
biomolecules (lipids, proteins, DNA) results in acute inflammation. However, without proper …

Conjugates of tetrapyrrolic macrocycles as potential anticancer target-oriented photosensitizers

AM Korolchuk, VA Zolottsev, AY Misharin - Topics in Current Chemistry, 2023 - Springer
Photodynamic therapy is a minimally invasive treatment of tumors using photosensitizers,
light, and reactive oxygen species, which can destroy cellular structures. With the …

Photodynamic Antimicrobial Activity of a Novel 5, 10, 15, 20-Tetrakis (4-Ethylphenyl) Porphyrin against Clinically Important Bacteria

F Espitia-Almeida, R Valle-Molinares… - Pharmaceuticals, 2023 - mdpi.com
The growing emergence of microbes resistant to commercially available antibiotic therapies
poses a threat to healthcare systems worldwide. Multiple factors have been associated with …

Sensitizers in photodynamic therapy

S Parab, PK Achalla, N Yanamandala, G Singhvi… - Nanomaterials for …, 2023 - Elsevier
Photodynamic therapy (PDT) is a treatment method, based on taking advantage of the
reactive oxygen species generated by irradiation of photosensitizers (PSs). Among various …

Gelatin nanoparticles via template polymerization for drug delivery system to photoprocess application in cells

AC Trindade, PARR de Castro, BCS Pinto… - Journal of …, 2022 - Taylor & Francis
Photodynamic therapy (PDT) is a clinical treatment based on the activation of light-
absorbing photosensitizers (PS) to generate reactive oxygen species, which are toxic to the …

Synthesis, photophysics, computational approaches, and biomolecule interactive studies of metalloporphyrins containing pyrenyl units: Influence of the metal center

C Hahn da Silveira, OA Chaves… - European Journal of …, 2022 - Wiley Online Library
A classical methodology to design free‐base meso‐tetra‐(1‐pyrenyl) porphyrin (H2TPyrP)
and their corresponding metalloporphyrins containing Zn (II), Cu (II), Ni (II), Co (III), and Mn …

Photosensitizer–peptoid conjugates for photoinactivation of Gram-negative bacteria: structure–activity relationship and mechanistic studies

W Yang, Y Yoon, Y Lee, H Oh, J Choi, S Shin… - Organic & …, 2021 - pubs.rsc.org
Multitarget engagement is considered an effective strategy to overcome the threat of
bacterial infection, and antimicrobials with multiple mechanisms of action have been …

Synthesis of 2‐Arylpyrimido[4,5‐b]porphyrins via Cyclization Reaction with Ammonia

A Singh, J Singh, M Nath - European Journal of Organic …, 2023 - Wiley Online Library
A facile synthetic strategy for the synthesis of a new series of β, β'‐fused 2‐arylpyrimido [4, 5‐
b] porphyrins has been developed by using condensation cyclization reaction with …