Advances in Hypoxia-Inducible Factor-1α Stabilizer Deferoxamine in Tissue Engineering

Y Zhu, B Chang, Y Pang, H Wang… - Tissue Engineering Part B …, 2023 - liebertpub.com
Deferoxamine (DFO) is an iron chelator with FDA approval for the clinical treatment of iron
excess. As a well-established stabilizer of hypoxia-inducible factor-1α (HIF-1α), DFO can …

Engineering tools for regulating hypoxia in tumour models

MH Kim, SD Green, CC Lin… - Journal of Cellular and …, 2021 - Wiley Online Library
Major advances in the field of genomic technologies have led to an improvement in cancer
diagnosis, classification and prognostication. However, many cancers remain incurable due …

[HTML][HTML] The integrative analysis of competitive endogenous RNA regulatory networks in osteoporosis

H Li, C Wang, Y Jin, Y Cai, H Sun, M Liu - Scientific Reports, 2022 - nature.com
Osteoporosis (OP) is a common bone disease of old age resulting from the imbalance
between bone resorption and bone formation. CircRNAs are a class of endogenous non …

[HTML][HTML] MicroRNAs may provide new strategies in the treatment and diagnosis of diabetic retinopathy: Importance of VEGF

VA Kordkheyli, MA Mishan, AK Tarsi… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Diabetic retinopathy (DR) is ocular microvascular complications of diabetes mellitus. Along
with the increasing prevalence of diabetes worldwide, DR has come into the major cause of …

[HTML][HTML] Correlation between ELF–PEMF exposure and human RPE cell proliferation, apoptosis and gene expression

M Oladnabi, MA Mishan, M Rezaeikanavi… - Journal of Ophthalmic …, 2021 - ncbi.nlm.nih.gov
Purpose Emerging evidence implies that electromagnetic fields (EMFs) can negatively affect
angiogenesis. In this regard, the effects of extremely low frequency pulsed electromagnetic …

[HTML][HTML] The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro

XX Gao, CH Liu, ZL Hu, HY Li, X Chang… - Frontiers in Bioscience …, 2021 - imrpress.com
Objective: Nucleus pulposus cells (NPCs) are cells extracted from the intervertebral disc and
are important for research into intervertebral disc degeneration (IVDD). NPCs live in an …

[PDF][PDF] Células tronco mesenquimais caninas cultivadas com desferroxamine (dfo) e interferon gamma, mimetizando condições de hipóxia e inflamação

PE Ocampo Ortiz - 2021 - repositorio.unesp.br
As células tronco mesenquimais (MSC) tem se destacado como candidatas ao uso em
terapias regenerativas. Porém, foi demonstrado que nem todas as condições clínicas …