Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus

J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …

[HTML][HTML] Acute coronary syndromes in diabetic patients, outcome, revascularization, and antithrombotic therapy

EE Babes, C Bustea, T Behl, MM Abdel-Daim… - Biomedicine & …, 2022 - Elsevier
Diabetes exacerbates the progression of atherosclerosis and is associated with increased
risk of developing acute coronary syndrome (ACS). Approximatively 25–30% of patients …

Effect of SGLT2-inhibitors on epicardial adipose tissue: a meta-analysis

W Masson, A Lavalle-Cobo, JP Nogueira - Cells, 2021 - mdpi.com
(1) Sodium–glucose cotransporter-2 inhibitors (SGLT2-i) reduce adipose tissue and
cardiovascular events in patients with type 2 diabetes (T2D). Accumulation of epicardial …

Exploring the multifaceted therapeutic potential of withaferin A and its derivatives

T Behl, A Sharma, L Sharma, A Sehgal, G Zengin… - Biomedicines, 2020 - mdpi.com
Withaferin A (WA), a manifold studied, C28-steroidal lactone withanolide found in Withania
somnifera. Given its unique beneficial effects, it has gathered attention in the era of modern …

Cardiovascular risk and statin therapy considerations in women

G Gheorghe, PP Toth, S Bungau, T Behl, M Ilie… - Diagnostics, 2020 - mdpi.com
Despite major progress in the prevention and treatment of cardiovascular diseases, women
remain an underdiagnosed and insufficiently treated group, with higher hospitalization and …

Early diagnosis of pancreatic cancer: the key for survival

G Gheorghe, S Bungau, M Ilie, T Behl, CM Vesa… - Diagnostics, 2020 - mdpi.com
Pancreatic cancer (PC) is one of the most aggressive forms of cancer. Negative prognosis is
mainly due to the late diagnosis in advanced stages, when the disease is already …

Notoginsenoside R1 attenuates oxidative stress‐induced osteoblast dysfunction through JNK signalling pathway

X Li, H Lin, X Zhang, RT Jaspers, Q Yu… - Journal of cellular …, 2021 - Wiley Online Library
Oxidative stress (OS)‐induced mitochondrial damage and the subsequent osteoblast
dysfunction contributes to the initiation and progression of osteoporosis. Notoginsenoside …

Exploring the therapeutic potential of phytochemicals in Alzheimer's disease: Focus on polyphenols and monoterpenes

I Piccialli, V Tedeschi, L Caputo, S D'Errico… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a chronic, complex neurodegenerative disorder mainly
characterized by the irreversible loss of memory and cognitive functions. Different …

Role of sodium glucose cotransporter type 2 inhibitors dapagliflozin on diabetic nephropathy in rats; Inflammation, angiogenesis and apoptosis

SK Elkazzaz, DM Khodeer, HM El Fayoumi… - Life Sciences, 2021 - Elsevier
Aims Diabetic nephropathy is a major cause of chronic kidney disease and end-stage renal
failure worldwide. Dapagliflozin Sodium-glucose co-transporter 2 (SGLT2) inhibitor is a new …

Interactions between leptin and insulin resistance in patients with prediabetes, with and without NAFLD

S Bungau, T Behl, DM Tit, F Banica… - Experimental and …, 2020 - spandidos-publications.com
This study explored the link between insulin sensitivity, insulin resistance and leptinaemia in
people with prediabetes with and without non‑alcoholic fatty liver disease (NAFLD). A total of …