The role of extracellular vesicles in cancer
R Kalluri, KM McAndrews - Cell, 2023 - cell.com
Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …
Exosome-based immunotherapy: a promising approach for cancer treatment
Z Xu, S Zeng, Z Gong, Y Yan - Molecular cancer, 2020 - Springer
In the era of the rapid development of cancer immunotherapy, there is a high level of interest
in the application of cell-released small vesicles that stimulate the immune system. As cell …
in the application of cell-released small vesicles that stimulate the immune system. As cell …
The tumor microenvironment: a milieu hindering and obstructing antitumor immune responses
A Labani-Motlagh, M Ashja-Mahdavi… - Frontiers in …, 2020 - frontiersin.org
The success of cancer immunotherapy relies on the knowledge of the tumor
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
microenvironment and the immune evasion mechanisms in which the tumor, stroma, and …
Engineered extracellular vesicles and their mimetics for cancer immunotherapy
C Liu, Y Wang, L Li, D He, J Chi, Q Li, Y Wu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) are heterogeneous membranous vesicles secreted by living
cells that are involved in many physiological and pathological processes as intermediaries …
cells that are involved in many physiological and pathological processes as intermediaries …
Advances in exosome-based drug delivery and tumor targeting: from tissue distribution to intracellular fate
J Shao, J Zaro, Y Shen - International journal of nanomedicine, 2020 - Taylor & Francis
Exosomes or small extracellular vesicles are considered a new generation of bioinspired-
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …
Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles
Extracellular vesicles (EVs) are gaining ground as next-generation drug delivery modalities.
Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability …
Genetic fusion of the protein of interest to a scaffold protein with high EV-sorting ability …
Cell‐specific targeting of extracellular vesicles through engineering the glycocalyx
W Zheng, R He, X Liang, S Roudi, J Bost… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are promising carriers for the delivery of a variety of chemical
and biological drugs. However, their efficacy is limited by the lack of cellular specificity …
and biological drugs. However, their efficacy is limited by the lack of cellular specificity …
Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity
S Liu, W Wang, S Hu, B Jia, B Tuo, H Sun… - Cell Death & …, 2023 - nature.com
Cancer immunotherapy has transformed traditional treatments, with immune checkpoint
blockade being particularly prominent. However, immunotherapy has minimal benefit for …
blockade being particularly prominent. However, immunotherapy has minimal benefit for …
Recent progress in exosome research: isolation, characterization and clinical applications
X Wang, J Xia, L Yang, J Dai, L He - Cancer Gene Therapy, 2023 - nature.com
Exosomes, a kind of nano-vesicles released by various cell types, carry a variety of “cargos”
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …
including proteins, RNAs, DNAs and lipids. There is substantial evidence that exosomes are …
Engineered extracellular vesicles for bone therapy
Extracellular vesicles, which are secreted by living cells and play a critical role in cellular
communication, have emerged as a promising cell-free strategy in the treatment of many …
communication, have emerged as a promising cell-free strategy in the treatment of many …