Enterococci as a One Health indicator of antimicrobial resistance

SZ Zaidi, R Zaheer, A Zovoilis… - Canadian Journal of …, 2024 - cdnsciencepub.com
The rapid increase of antimicrobial-resistant bacteria in humans and livestock is concerning.
Antimicrobials are essential for the treatment of disease in modern day medicine, and their …

Synergistic combination of linezolid and fosfomycin closing each other's mutant selection window to prevent enterococcal resistance

L Jiang, N Xie, M Chen, Y Liu, S Wang, J Mao… - Frontiers in …, 2021 - frontiersin.org
Enterococci, the main pathogens associated with nosocomial infections, are resistant to
many common antibacterial drugs including β-lactams, aminoglycosides, etc. Combination …

Unraveling Mechanisms and Epidemic Characteristics of Nitrofurantoin Resistance in Uropathogenic Enterococcus faecium Clinical Isolates

Y Zhang, L Wang, C Zhou, Y Lin, S Liu… - Infection and Drug …, 2021 - Taylor & Francis
Purpose Multidrug-resistant (MDR) Enterococcus faecium is an important nosocomial
pathogen causing urinary tract infection, and the reapplication of nitrofurantoin (NIT) in the …

Determination of epidemiological cutoff values for antimicrobial resistance of Enterococcus cecorum

J Laurentie, G Mourand, P Grippon… - Journal of Clinical …, 2023 - Am Soc Microbiol
Enterococcus cecorum, a commensal Gram-positive bacterium of the chicken gut, has
emerged as a worldwide cause of lameness in poultry, particularly in fast-growing broilers. It …

Molecular Mechanisms and Epidemiology of Fosfomycin Resistance in Staphylococcus aureus Isolated From Patients at a Teaching Hospital in China

W Xu, T Chen, H Wang, W Zeng, Q Wu, K Yu… - Frontiers in …, 2020 - frontiersin.org
Staphylococcus aureus is a major cause of hospital-and community-acquired infections
placing a significant burden on the healthcare system. With the widespread of multidrug …

Dose Optimization of Combined Linezolid and Fosfomycin against Enterococcus by Using an In Vitro Pharmacokinetic/Pharmacodynamic Model

J Mao, T Li, N Zhang, S Wang, Y Li, Y Peng… - Microbiology …, 2021 - Am Soc Microbiol
The rapid spread of antibiotic resistance among Enterococcus has prompted considerable
interest in determining the dosage regimen of linezolid combined with fosfomycin. A …

Pharmacodynamics of Linezolid Plus Fosfomycin Against Vancomycin–Resistant Enterococcus faecium in a Hollow Fiber Infection Model

S Wang, H Liu, J Mao, Y Peng, Y Yan, Y Li… - Frontiers in …, 2021 - frontiersin.org
The optimal therapy for severe infections caused by vancomycin-resistant Enterococcus
faecium (VREfm) remains unclear, but the combination of linezolid and fosfomycin may be a …

High Prevalence and Overexpression of Fosfomycin-Resistant Gene fosX in Enterococcus faecium From China

L Xin, X Xu, Q Shi, R Han, J Wang, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Enterococc i are one of the main causes of gastrointestinal tract infections in the healthcare
system and can develop resistance to fosfomycin through plasmid or chromosomally …

[HTML][HTML] Asp50Glu mutation in MurA results in fosfomycin resistance in Enterococcus faecium

L Xin, Z Hu, R Han, X Xu, C Wang, D Li, Y Guo… - Journal of Global …, 2022 - Elsevier
Objectives Enterococcus faecium is one of the important pathogens causing nosocomial
infection, which can be resistant to fosfomycin by obtaining the plasmid-encoded fosfomycin …

First Report of the Plasmid-mediated fosB Gene in Enterococcus faecalis from Pigs

X Wang, Y Gao, X Liu, N Sun, J Huang, L Wang - Genes, 2021 - mdpi.com
Plasmid-mediated fosfomycin determinants is a global public health concern due to the
increasing dissemination of fosfomycin resistance and limited clinical treatment options …