Tendon-bone insertion injuries (TBI), such as anterior cruciate ligament (ACL) and rotator
cuff injuries, are common degenerative or traumatic pathologies with a negative impact on …

Living organisms in nature have undergone continuous evolution over billions of years,
resulting in the formation of high-performance fracture-resistant biomineralized tissues such …

Osteoimmunology and immune microenvironments play an important role in bone tissue
regeneration. Efficient and timely activation of pro-regenerative macrophages (M2) at the …

Tendon-bone insertion (TBI) injuries are common, primarily involving the rotator cuff (RC)
and anterior cruciate ligament (ACL). At present, repair surgery and reconstructive surgery …

Bone mineralization is a ubiquitous process among vertebrates that involves a dynamic
physical/chemical interplay between the organic and inorganic components of bone tissues …

Purinergic signaling is a key molecular pathway in the maintenance of bone health and
regeneration. P1 receptor signaling, which is activated by extracellular adenosine, has …

Revascularization after rotator cuff repair is crucial for tendon‐to‐bone healing. The chirality
of materials has been reported to influence their performance in tissue repair. However, data …

The healing process of critical-sized bone defects urges for a suitable biomineralization
environment. However, the unsatisfying repair outcome usually results from a disturbed …

Calcium phosphate-based biomineralized biomaterials have broad application prospects.
However, the immune response and foreign body reactions elicited by biomineralized …

Purpose To compare the effects of anatomical preservation (AP) and interpositional
preservation (IP) of subacromial bursa tissue on tendon-to-bone healing in a rat model of …