An epigenetic role of mitochondria in cancer
Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …
Protein O-GlcNAcylation: emerging mechanisms and functions
O-GlcNAcylation—the attachment of O-linked N-acetylglucosamine (O-GlcNAc) moieties to
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
cytoplasmic, nuclear and mitochondrial proteins—is a post-translational modification that …
Metabolic reprogramming and epigenetic modifications on the path to cancer
L Sun, H Zhang, P Gao - Protein & cell, 2022 - academic.oup.com
Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …
regulate each other, are among the well-known cancer hallmarks. Recent evidence …
Endothelial cell metabolism
G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
active players in the formation of new blood vessels (angiogenesis) both in health and (life …
Nutrient regulation of signaling and transcription
GW Hart - Journal of Biological Chemistry, 2019 - ASBMB
In the early 1980s, while using purified glycosyltransferases to probe glycan structures on
surfaces of living cells in the murine immune system, we discovered a novel form of …
surfaces of living cells in the murine immune system, we discovered a novel form of …
Epigenetic mechanisms of immune remodeling in sepsis: targeting histone modification
D Wu, Y Shi, H Zhang, C Miao - Cell death & disease, 2023 - nature.com
Sepsis is a life-threatening disorder disease defined as infection-induced dysregulated
immune responses and multiple organ dysfunction. The imbalance between …
immune responses and multiple organ dysfunction. The imbalance between …
Metabolism and epigenetics at the heart of T cell function
L Soriano-Baguet, D Brenner - Trends in immunology, 2023 - cell.com
T cell subsets adapt and rewire their metabolism according to their functions and
surrounding microenvironment. Whereas naive T cells rely on mitochondrial metabolic …
surrounding microenvironment. Whereas naive T cells rely on mitochondrial metabolic …
The sugar-signaling hub: overview of regulators and interaction with the hormonal and metabolic network
S Sakr, M Wang, F Dédaldéchamp… - International journal of …, 2018 - mdpi.com
Plant growth and development has to be continuously adjusted to the available resources.
Their optimization requires the integration of signals conveying the plant metabolic status, its …
Their optimization requires the integration of signals conveying the plant metabolic status, its …
Parental advisory: maternal and paternal stress can impact offspring neurodevelopment
Parental stress exposures are implicated in the risk for offspring neurodevelopmental and
neuropsychiatric disorders, prompting critical examination of preconception and prenatal …
neuropsychiatric disorders, prompting critical examination of preconception and prenatal …
The omniscient placenta: metabolic and epigenetic regulation of fetal programming
Fetal development could be considered a sensitive period wherein exogenous insults and
changes to the maternal milieu can have long-term impacts on developmental programming …
changes to the maternal milieu can have long-term impacts on developmental programming …