After asthma: redefining airways diseases
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …
costs. Substantial progress was made against key outcomes such as hospital admissions …
The asthma–COPD overlap syndrome
DS Postma, KF Rabe - New England Journal of Medicine, 2015 - Mass Medical Soc
The Asthma–COPD Overlap Syndrome | NEJM Skip to main content NEJM Group Follow Us
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …
Facebook Twitter Instagram YouTube LinkedIn Prepare to become a physician, build your …
[HTML][HTML] Dupilumab for COPD with type 2 inflammation indicated by eosinophil counts
Background In some patients with chronic obstructive pulmonary disease (COPD), type 2
inflammation may increase exacerbation risk and may be indicated by elevated blood …
inflammation may increase exacerbation risk and may be indicated by elevated blood …
[HTML][HTML] Mepolizumab for eosinophilic chronic obstructive pulmonary disease
Background Patients with chronic obstructive pulmonary disease (COPD) with an
eosinophilic phenotype may benefit from treatment with mepolizumab, a monoclonal …
eosinophilic phenotype may benefit from treatment with mepolizumab, a monoclonal …
Treatable traits: toward precision medicine of chronic airway diseases
A Agusti, E Bel, M Thomas… - European …, 2016 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic
airway diseases that have a high personal and social impact. They likely represent a …
airway diseases that have a high personal and social impact. They likely represent a …
Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease …
S Pascoe, N Locantore, MT Dransfield… - The lancet Respiratory …, 2015 - thelancet.com
Background The short-term benefits of inhaled corticosteroids for patients with chronic
obstructive pulmonary disease (COPD) are greater in patients with evidence of eosinophilic …
obstructive pulmonary disease (COPD) are greater in patients with evidence of eosinophilic …
Airway inflammation in COPD: progress to precision medicine
C Brightling, N Greening - European Respiratory Journal, 2019 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is a significant cause of morbidity and
mortality worldwide, and its prevalence is increasing. Airway inflammation is a consistent …
mortality worldwide, and its prevalence is increasing. Airway inflammation is a consistent …
Blood eosinophils and exacerbations in chronic obstructive pulmonary disease. The Copenhagen General Population Study
S Vedel-Krogh, SF Nielsen, P Lange… - American journal of …, 2016 - atsjournals.org
Rationale: Whether high blood eosinophils are associated with chronic obstructive
pulmonary disease (COPD) exacerbations among individuals with COPD in the general …
pulmonary disease (COPD) exacerbations among individuals with COPD in the general …
Eosinophilic inflammation in COPD: prevalence and clinical characteristics
D Singh, U Kolsum, CE Brightling… - European …, 2014 - Eur Respiratory Soc
Eosinophilic inflammation is thought to be a characteristic feature of asthma rather than
COPD. However, studies have shown that a subset of COPD patients with eosinophilic …
COPD. However, studies have shown that a subset of COPD patients with eosinophilic …
[HTML][HTML] Benralizumab for the prevention of COPD exacerbations
GJ Criner, BR Celli, CE Brightling… - … England Journal of …, 2019 - Mass Medical Soc
Background The efficacy and safety of benralizumab, an interleukin-5 receptor alpha–
directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with …
directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with …