Mammalian in vitro gametogenesis
M Saitou, K Hayashi - Science, 2021 - science.org
BACKGROUND Mammalian germ cells differentiate into oocytes in females and
spermatozoa in males. An oocyte and a spermatozoon fuse to form a zygote and then …
spermatozoa in males. An oocyte and a spermatozoon fuse to form a zygote and then …
Ubiquitin ligases: guardians of mammalian development
DA Cruz Walma, Z Chen, AN Bullock… - … Reviews Molecular Cell …, 2022 - nature.com
Mammalian development demands precision. Millions of molecules must be properly
located in temporal order, and their function regulated, to orchestrate important steps in cell …
located in temporal order, and their function regulated, to orchestrate important steps in cell …
The adult human testis transcriptional cell atlas
Human adult spermatogenesis balances spermatogonial stem cell (SSC) self-renewal and
differentiation, alongside complex germ cell-niche interactions, to ensure long-term fertility …
differentiation, alongside complex germ cell-niche interactions, to ensure long-term fertility …
Phthalate-induced testosterone/androgen receptor pathway disorder on spermatogenesis and antagonism of lycopene
Y Zhao, XN Li, H Zhang, JG Cui, JX Wang… - Journal of Hazardous …, 2022 - Elsevier
Male infertility is an attracting growing concern owing to decline in sperm quality of men
worldwide. Phthalates, in particular to di (2-ethylhexyl) phthalate (DEHP) or its main …
worldwide. Phthalates, in particular to di (2-ethylhexyl) phthalate (DEHP) or its main …
The role of the epididymis and the contribution of epididymosomes to mammalian reproduction
It is well-established that testicular spermatozoa are immature and acquire motility and
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …
Some of the factors involved in male infertility: a prospective review
E Babakhanzadeh, M Nazari… - … journal of general …, 2020 - Taylor & Francis
Infertility is defined as the inability of couples to have a baby after one year of regular
unprotected intercourse, affecting 10 to 15% of couples. According to the latest WHO …
unprotected intercourse, affecting 10 to 15% of couples. According to the latest WHO …
[HTML][HTML] Coronavirus disease-19 and fertility: viral host entry protein expression in male and female reproductive tissues
KE Stanley, E Thomas, M Leaver, D Wells - Fertility and sterility, 2020 - Elsevier
Objective To identify cell types in the male and female reproductive systems at risk for SARS-
CoV-2 infection because of the expression of host genes and proteins used by the virus for …
CoV-2 infection because of the expression of host genes and proteins used by the virus for …
In vitro reconstitution of the whole male germ-cell development from mouse pluripotent stem cells
Mammalian male germ-cell development consists of three distinct phases: primordial germ
cell (PGC) development, male germ-cell specification for spermatogonium development …
cell (PGC) development, male germ-cell specification for spermatogonium development …
Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis
Spermatogenesis is a differentiation process during which diploid spermatogonial stem cells
(SSCs) produce haploid spermatozoa. This highly specialized process is precisely …
(SSCs) produce haploid spermatozoa. This highly specialized process is precisely …
Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis
A systematic interrogation of male germ cells is key to complete understanding of molecular
mechanisms governing spermatogenesis and the development of new strategies for …
mechanisms governing spermatogenesis and the development of new strategies for …