Advances in islet encapsulation technologies
Type 1 diabetes is an autoimmune disorder in which the immune system attacks and
destroys insulin-producing islet cells of the pancreas. Although islet transplantation has …
destroys insulin-producing islet cells of the pancreas. Although islet transplantation has …
Discovering cell-adhesion peptides in tissue engineering: beyond RGD
As an alternative to natural extracellular matrix (ECM) macromolecules, cell-adhesion
peptides (CAPs) have had tremendous impact on the design of cell culture platforms …
peptides (CAPs) have had tremendous impact on the design of cell culture platforms …
3D Bioprinting of shear-thinning hybrid bioinks with excellent bioactivity derived from gellan/alginate and thixotropic magnesium phosphate-based gels
Y Chen, X Xiong, X Liu, R Cui, C Wang… - Journal of Materials …, 2020 - pubs.rsc.org
3D Bioprinting is expected to become a strong tool for regenerative medicine, but
satisfactory bioinks for the printing of constructs containing living cells are lacking due to the …
satisfactory bioinks for the printing of constructs containing living cells are lacking due to the …
Hydrogels in emerging technologies for type 1 diabetes
Type 1 diabetes therapies that afford tighter glycemic control in a more manageable and
painless manner for patients has remained a central focus of next-generation diabetes …
painless manner for patients has remained a central focus of next-generation diabetes …
Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine
R Subbiah, RE Guldberg - Advanced healthcare materials, 2019 - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …
A century-long journey from the discovery of insulin to the implantation of stem cell–derived islets
A Ramzy, PJ Belmonte, MJS Braam, S Ida… - Endocrine …, 2023 - academic.oup.com
For the past century, insulin injections have saved millions of lives, but glycemic instability is
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …
Advances in encapsulation and delivery strategies for islet transplantation
Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease caused by the destruction of
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …
pancreatic β‐cells in response to autoimmune reactions. Shapiro et al. conducted novel islet …
[HTML][HTML] Engineered 3D hydrogels with full-length fibronectin that sequester and present growth factors
Extracellular matrix (ECM)-derived matrices such as Matrigel are used to culture numerous
cell types in vitro as they recapitulate ECM properties that support cell growth, organisation …
cell types in vitro as they recapitulate ECM properties that support cell growth, organisation …
Biomaterials for personalized cell therapy
Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …
treatments for previously intractable diseases. Notable examples include mesenchymal …
[HTML][HTML] Type 1 diabetes and engineering enhanced islet transplantation
The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …