Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical Reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Redox regulation of the immune response
G Morris, M Gevezova, V Sarafian… - Cellular & Molecular …, 2022 - nature.com
The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …
Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
LK Billingham, JS Stoolman, K Vasan… - Nature …, 2022 - nature.com
The NLRP3 inflammasome is linked to sterile and pathogen-dependent inflammation, and
its dysregulation underlies many chronic diseases. Mitochondria have been implicated as …
its dysregulation underlies many chronic diseases. Mitochondria have been implicated as …
Emerging connectivity of programmed cell death pathways and its physiological implications
S Bedoui, MJ Herold, A Strasser - Nature reviews Molecular cell biology, 2020 - nature.com
The removal of functionally dispensable, infected or potentially neoplastic cells is driven by
programmed cell death (PCD) pathways, highlighting their important roles in homeostasis …
programmed cell death (PCD) pathways, highlighting their important roles in homeostasis …
Aggregation-induced emission (AIE), life and health
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …
luminescent agents and imaging techniques currently being used to assess health and treat …
Inflammatory mechanisms contributing to endothelial dysfunction
Maintenance of endothelial cell integrity is an important component of human health and
disease since the endothelium can perform various functions including regulation of …
disease since the endothelium can perform various functions including regulation of …
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes
AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …
Recent progress in fluorescent probes for bacteria
Y Huang, W Chen, J Chung, J Yin, J Yoon - Chemical Society Reviews, 2021 - pubs.rsc.org
Food fermentation, antibiotics, and pollutant degradation are closely related to bacteria.
Bacteria play an irreplaceable role in life. However, some bacteria seriously threaten human …
Bacteria play an irreplaceable role in life. However, some bacteria seriously threaten human …
NLRP3 inflammasome in endothelial dysfunction
B Bai, Y Yang, QI Wang, M Li, C Tian, Y Liu… - Cell death & …, 2020 - nature.com
Inflammasomes are a class of cytosolic protein complexes. They act as cytosolic innate
immune signal receptors to sense pathogens and initiate inflammatory responses under …
immune signal receptors to sense pathogens and initiate inflammatory responses under …
The NLRP3 inflammasome: an overview of mechanisms of activation and regulation
N Kelley, D Jeltema, Y Duan, Y He - International journal of molecular …, 2019 - mdpi.com
The NLRP3 inflammasome is a critical component of the innate immune system that
mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in …
mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in …