Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Background: Meta-analysis of randomized studies using lysergic acid diethylamide (LSD) for
alcohol use disorder (AUD) showed large, significant effects for LSD efficacy compared to …

Introduction: As their name suggests,'psychedelic'(mind-revealing) compounds are thought
to catalyse processes of psychological insight; however, few satisfactory scales exist to …

After a two-decade hiatus in which research on psychedelics was essentially halted,
placebo-controlled clinical trials of psychedelic-assisted therapy for mental health conditions …

Objective To explore whether psilocybin with psychological support modulates personality
parameters in patients suffering from treatment‐resistant depression (TRD). Method Twenty …

Scientific interest in serotonergic psychedelics (eg, psilocybin and LSD; 5‐HT2A receptor
agonists) has dramatically increased within the last decade. Clinical studies administering …

Psychedelics make up a group of psychoactive compounds that induce hallucinogenic
effects by activating the serotonin 2A receptor (5-HT2AR). Clinical trials have demonstrated …

This chapter begins with a brief review of descriptions and definitions of mystical-type
experiences and the historical connection between classic hallucinogens and mystical …

Psilocybin shows efficacy to alleviate depression in human clinical trials for six or more
months after only one or two treatments. Another hallucinogenic drug, esketamine, has …

Background Psilocybin therapy has shown promise as a rapid-acting treatment for
depression, anxiety, and demoralization in patients with serious medical illness (eg, cancer) …