[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation

CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

Mitochondrial-derived vesicles: the good, the bad, and the ugly

A Picca, F Guerra, R Calvani, HJ Coelho-Júnior… - International Journal of …, 2023 - mdpi.com
Mitophagy is crucial for maintaining mitochondrial quality. However, its assessment in vivo is
challenging. The endosomal–lysosomal system is a more accessible pathway through …

Mitochondria-derived vesicles and their potential roles in kidney stone disease

S Chaiyarit, V Thongboonkerd - Journal of translational medicine, 2023 - Springer
Recent evidence has shown significant roles of mitochondria-derived vesicles (MDVs) in
mitochondrial quality control (MQC) system. Under mild stress condition, MDVs are formed …

The crosstalk between mitochondrial quality control and metal-dependent cell death

Q Zhou, C Ren, J Li, L Wang, Y Duan, R Yao… - Cell Death & …, 2024 - nature.com
Mitochondria are the centers of energy and material metabolism, and they also serve as the
storage and dispatch hubs of metal ions. Damage to mitochondrial structure and function …

Honokiol, an inducer of sirtuin‐3, protects against non‐steroidal anti‐inflammatory drug‐induced gastric mucosal mitochondrial pathology, apoptosis and inflammatory …

S Debsharma, S Pramanik, S Bindu… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Mitochondrial oxidative stress, inflammation and apoptosis
primarily underlie gastric mucosal injury caused by the widely used non‐steroidal anti …

Induction of mitochondrial toxicity by non-steroidal anti-inflammatory drugs (NSAIDs): The ultimate trade-off governing the therapeutic merits and demerits of these …

S Mazumder, S Bindu, S Debsharma… - Biochemical …, 2024 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are most extensively used over-the-counter
FDA-approved analgesic medicines for treating inflammation, musculoskeletal pain, arthritis …

[HTML][HTML] The Role of Polyphenols in Modulating Mitophagy: Implications for Therapeutic Interventions

X Lin, W Liu, X Hu, Z Liu, F Wang, J Wang - Pharmacological Research, 2024 - Elsevier
This review rigorously assesses the burgeoning research into the role of polyphenols in
modulating mitophagy, an essential cellular mechanism for the targeted removal of impaired …

A Comprehensive Pan-Cancer Analysis of Cytochrome C Oxidase Assembly Factor 1 (COA1) Reveals Instrumental Role of Mitochondrial Protein Assembly in Cancer …

S Ghosh, D Goswami, R Dutta, D Ghatak… - Cell Biochemistry and …, 2024 - Springer
Cytochrome c oxidase assembly factor 1 (COA1), a mitochondrial respiratory chain complex
assembly factor protein of inner mitochondrial membrane (IMM), is involved in translating …

Synthesis, DFT, and in silico biological evaluation of chalcone bearing pyrazoline ring against Helicobacter pylori receptors

NA Alshaye, NS Alharbi, MA El-Atawy, RO El-Zawawy… - Heliyon, 2024 - cell.com
Peptic ulcer disease (PUD), often caused by Helicobacter pylori infection, is a prevalent
gastrointestinal condition characterized by the erosion of the gastric or duodenal mucosal …

Effect of a 12-Week Walking Program Monitored by Global Physical Capacity Score (GPCS) on Circulating Cell-Free mtDNA and DNase Activity in Patients with …

G Chimienti, F Russo, A Bianco, F Maqoud… - International Journal of …, 2024 - mdpi.com
Irritable bowel syndrome (IBS) involves low-grade mucosal inflammation. Among the various
approaches capable of managing the symptoms, physical activity is still under investigation …