Myocardial ischemia-reperfusion injury and the influence of inflammation
Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to
ischemia in the corresponding myocardial territory which generally results in myocardial …
ischemia in the corresponding myocardial territory which generally results in myocardial …
[HTML][HTML] Cells of the immune system in cardiac remodeling: main players in resolution of inflammation and repair after myocardial infarction
I Kologrivova, M Shtatolkina, T Suslova… - Frontiers in …, 2021 - frontiersin.org
The burden of heart failure (HF), developing after myocardial infarction MI, still represents a
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …
Macrophages in cardiac remodelling after myocardial infarction
J Yap, J Irei, J Lozano-Gerona, S Vanapruks… - Nature Reviews …, 2023 - nature.com
Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …
Immune cells and immunotherapy for cardiac injury and repair
Cardiac injury remains a major cause of morbidity and mortality worldwide. Despite
significant advances, a full understanding of why the heart fails to fully recover function after …
significant advances, a full understanding of why the heart fails to fully recover function after …
[HTML][HTML] Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer
Macrophages are the most important phagocytes in vivo. However, the tumor
microenvironment can affect the function and polarization of macrophages and form tumor …
microenvironment can affect the function and polarization of macrophages and form tumor …
Nanowired human cardiac organoid transplantation enables highly efficient and effective recovery of infarcted hearts
Human cardiac organoids hold remarkable potential for cardiovascular disease modeling
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
and human pluripotent stem cell–derived cardiomyocyte (hPSC-CM) transplantation. Here …
[HTML][HTML] Therapeutic delivery of microRNA-125a-5p oligonucleotides improves recovery from myocardial ischemia/reperfusion injury in mice and swine
L Gao, F Qiu, H Cao, H Li, G Dai, T Ma, Y Gong… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Clinical application of mesenchymal stem cells (MSCs) and MSC-derived
exosomes (MSC-Exos) to alleviate myocardial ischemia/reperfusion (I/R) injury is …
exosomes (MSC-Exos) to alleviate myocardial ischemia/reperfusion (I/R) injury is …
Targeting cardiac fibrosis in heart failure with preserved ejection fraction: mirage or miracle?
Cardiac fibrosis is central to the pathology of heart failure, particularly heart failure with
preserved ejection fraction (HF p EF). Irrespective of the underlying profibrotic condition (eg …
preserved ejection fraction (HF p EF). Irrespective of the underlying profibrotic condition (eg …
Role of inflammatory chemokines in hypertension
TP Mikolajczyk, P Szczepaniak, F Vidler… - Pharmacology & …, 2021 - Elsevier
Hypertension is associated with immune cells activation and their migration into the kidney,
vasculature, heart and brain. These inflammatory mechanisms are critical for blood pressure …
vasculature, heart and brain. These inflammatory mechanisms are critical for blood pressure …
[HTML][HTML] Macrophage polarization in cardiac tissue repair following myocardial infarction
Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a …
creating a substantial socio-economic burden as a result. Myocardial infarction is a …