Uncontrolled noncompressible hemorrhage is a major cause of mortality following traumatic
injuries in civilian and military populations. An injectable hemostat for point-of-care treatment …

Sepsis and trauma are both leading causes of death in the United States and represent
major public health challenges. Murine models have largely been used in sepsis and …

Contemporary trauma care comprises advanced pre-hospital care, regionalized trauma
systems, damage control operative techniques, advanced critical care, rehabilitation with …

BACKGROUND Historically, hemorrhage has been attributed as the leading cause (40%) of
early death. However, a rigorous, real-time classification of the cause of death (COD) has …

Trauma is a pressing public health epidemic. In 2016 alone, trauma accounted for 29.2
million emergency department visits and 39.5 million physician office visits in the United …

Importance Prehospital plasma administration improves survival in injured patients at risk for
hemorrhagic shock and transported by air ambulance. Traumatic brain injury (TBI) is a …

Abstract Background National Blood Collection and Utilization Surveys (NBCUS) have
reported decreases in US blood collections and transfusions since 2008. The declines …

Prognosis of the long-term functional outcome of traumatic brain injury is essential for
personalized management of that injury. Nonetheless, accurate prediction remains …

Methods Retrospective, cross-sectional and matched case-control study designs have
commonly been used to analyze outcomes such as mortality, length of stay, and …

Background: Choosing the appropriate endpoint for a trauma hemorrhage control trial can
determine the likelihood of its success. Recent Phase 3 trials and observational studies …