Background The hemostatic properties of tranexamic acid (TXA) are well described, but the
immunological effects of TXA administration after traumatic injury have not been thoroughly …

Methods We performed a secondary analysis using a harmonized data set derived from two
recent prehospital plasma randomized trials. Identical inclusion/exclusion criteria and …

As the leading global cause of death among youth and young adults, the impact of trauma
on years of productive life lost cannot be overstated. 1 With only brain injury as a larger …

Background Trauma systems currently rely on imperfect and subjective tools to prioritize
responses and resources, thus there is a critical need to develop a more accurate trauma …

Detection and severity assessment of subdural hematoma is a major step in the evaluation
of traumatic brain injuries. This is a retrospective study of 110 computed tomography (CT) …

BACKGROUND Coagulopathy is a common complication after severe trauma. The efficacy
of 4-factor prothrombin complex concentrate (4-PCC) as an adjunct to fresh frozen plasma …

Background Both early detection and severity assessment of liver trauma are critical for
optimal triage and management of trauma patients. Current trauma protocols utilize …

Background Major trauma is associated with high incidence of septic complications and
multiple organ dysfunction (MOD), which markedly influence the outcome of injured patients …

Polytraumatic injuries, specifically long bone fracture and traumatic brain injury (TBI),
frequently occur together. Clinical observation has long held that TBI can accelerate fracture …

Background Traumatic injury is the third leading cause of death overall. To optimize the
outcomes in these patients, hospitals employ whole-body computed tomography (WBCT) …