Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …

Pathological cardiac remodeling normally involves changes in structure, function, and
energy metabolism of the heart induced by cardiac injury or load, terminally leading to heart …

Inflammation resolution is important for scar formation following myocardial infarction (MI)
and requires the coordinated actions of macrophages and fibroblasts. In this study, we …

Healing of myocardial infarction (MI) requires monocytes/macrophages. These mononuclear
phagocytes likely degrade released macromolecules and aid in scavenging of dead …

We present use of a synthetic, injectable matrix metalloproteinase (MMP)-responsive,
bioactive hydrogel as an in situ forming scaffold to deliver thymosin β4 (Tβ4), a pro …

Biomaterials is a multidisciplinary subject involving materials science, engineering, cell
biology, and medicine. This textbook provides an appropriate balance between depth and …

Induced pluripotent stem (iPS) cells are being used increasingly to complement their
embryonic counterparts to understand and develop the therapeutic potential of pluripotent …

Chronic isoproterenol administration produces a rapid, highly reproducible rodent model of
cardiac hypertrophy. Yet, despite widespread use of this model, the effects of isoproterenol …

Imaging modalities such as micro‐computed tomography (micro‐CT), micro‐positron
emission tomography (micro‐PET), high‐resolution MRI, optical imaging, and high …

Aims Cardiomyocyte β2-adrenergic receptor (β2AR) cyclic adenosine monophosphate
(cAMP) signalling is regulated by the receptors' subcellular location within transverse …