The burden of heart failure (HF), developing after myocardial infarction MI, still represents a
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …

During microbial infection, pre-existing memory CD8+ T cells that are not specific for the
infecting pathogens can be activated by cytokines without cognate antigens, termed …

Neutrophils perform critical functions in the innate response to infection, including through
the production of neutrophil extracellular traps (NETs)-web-like DNA structures which are …

Inflammatory bowel disease (IBD) is one relapsing and lifelong disease that affects millions
of patients worldwide. Increasing evidence has recently highlighted immune-system …

During viral infections, significant numbers of T cells are activated in a T cell receptor-
independent and cytokine-dependent manner, a phenomenon referred to as “bystander …

Stimulator of interferon genes (STING) was initially described as a sensor of intracellular
bacterial and viral DNA and a promising adjuvant target in innate immune cells; more …

T cells are the central mediators of both humoral and cellular adaptive immune responses.
Highly specific receptor-mediated clonal selection and expansion of T cells assure antigen …

A large body of evidence produced during decades of research indicates that myocardial
injury activates innate immunity. On the one hand, innate immunity both aggravates …

The current paradigm of onset and progression of periodontitis includes oral dysbiosis
directed by inflammophilic bacteria, leading to altered resolution of inflammation and lack of …

Over the last few years, we have seen an increasing interest and demand for pigs in
biomedical research. Domestic pigs (Sus scrofa domesticus) are closely related to humans …