Molecular dynamics of the viral life cycle: progress and prospects

PE Jones, C Pérez-Segura, AJ Bryer, JR Perilla… - Current opinion in …, 2021 - Elsevier
Highlights•Molecular dynamics simulations are the central technique uniting the field of
computational virology.•Viruses responsible for recent epidemics and pandemics have been …

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for …

ET Baldwin, M Götte, EP Tchesnokov… - Proceedings of the …, 2022 - National Acad Sciences
Human endogenous retroviruses (HERVs) comprise nearly 8% of the human genome and
are derived from ancient integrations of retroviruses into the germline. The biology of HERVs …

Sagacious epitope selection for vaccines, and both antibody-based therapeutics and diagnostics: tips from virology and oncology

SKE Gan, SX Phua, JY Yeo - Antibody Therapeutics, 2022 - academic.oup.com
The target of an antibody plays a significant role in the success of antibody-based
therapeutics and diagnostics, and vaccine development. This importance is focused on the …

Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

D Chaudhary, A Singh, M Marzuki, A Ghosh… - Scientific Reports, 2022 - nature.com
There is an urgent need to validate new drug targets and identify small molecules that
possess activity against both drug-resistant and drug-sensitive bacteria. The enzymes …

[PDF][PDF] Sagacious epitope selection and the things about them that matter in vaccines, 1 and both antibody-based therapeutics and diagnostics, with lessons from …

SKE Gan, SX Phua, JY Yeo - oncology, 2021 - researchgate.net
Review: Sagacious epitope selection and the things about them that matter in vaccines, 1
and both antibody-based therapeutics an Page 1 Review: Sagacious epitope selection and …

[引用][C] Innovative and affordable HIV-1 drug resistance testing for resource limited settings.

SC Manyana - 2022