H3Africa: current perspectives

N Mulder, A Abimiku, SN Adebamowo… - Pharmacogenomics …, 2018 - Taylor & Francis
Precision medicine is being enabled in high-income countries by the growing availability of
health data, increasing knowledge of the genetic determinants of disease and variation in …

[HTML][HTML] Five priorities of African genomics research: the next frontier

A Wonkam, NS Munung, C Dandara… - Annual Review of …, 2022 - annualreviews.org
To embrace the prospects of accurately diagnosing thousands of monogenic conditions,
predicting disease risks for complex traits or diseases, tailoring treatment to individuals' …

[HTML][HTML] Democratizing clinical-genomic data: How federated platforms can promote benefits sharing in genomics

M Alvarellos, HE Sheppard, I Knarston… - Frontiers in …, 2023 - frontiersin.org
Since the first sequencing of the human genome, associated sequencing costs have
dramatically lowered, leading to an explosion of genomic data. This valuable data should in …

Human OMICs and computational biology research in Africa: current challenges and prospects

Y Hamdi, L Zass, H Othman, F Radouani… - OMICS: A Journal of …, 2021 - liebertpub.com
Following the publication of the first human genome, OMICs research, including genomics,
transcriptomics, proteomics, and metagenomics, has been on the rise. OMICs studies …

[HTML][HTML] Role of a regulatory and governance framework in human biological materials and data sharing in National Biobanks: Case studies from Biobank Integrating …

H Nansumba, I Ssewanyana, M Tai… - Wellcome Open …, 2019 - ncbi.nlm.nih.gov
Background: In the last decade, Low-and Middle-Income Countries (LMICs) have set up
Biobanks to collect human biological materials and associated data for genomic research …

Brain banking in low and middle-income countries: raison d'être for the Ibadan brain ageing, dementia and neurodegeneration (IBADAN) brain bank project

RO Akinyemi, A Salami, J Akinyemi, A Ojagbemi… - Brain research …, 2019 - Elsevier
Brain banks are biorepositories of central nervous system (CNS) tissue including fixed and
frozen whole brains, brain biopsies and spinal cord, as well as body fluids comprising the …

Biospecimens and biobanking in global health

M Mendy, RT Lawlor, AL van Kappel… - Clinics in …, 2018 - labmed.theclinics.com
Infectious diseases continue to be a major burden of disease globally. According to the
Global Burden of Disease Study 2015, although the epidemic of human immunodeficiency …

Biobanking in a challenging African environment: Unique experience from the SIREN project

RO Akinyemi, K Akinwande, S Diala… - Biopreservation and …, 2018 - liebertpub.com
Africa was previously insufficiently represented in the emerging discipline of biobanking
despite commendable early efforts. However, with the Human, Heredity, and Health in Africa …

Unraveling the ethical, legal, and social implications of neurobiobanking and stroke genomic research in Africa: a Study Protocol of the African Neurobiobank for …

RO Akinyemi, C Jenkins, M Nichols… - … journal of qualitative …, 2020 - journals.sagepub.com
The ethical, legal, and social implications (ELSI) of emerging neurobiobanks and data
resources are unclear in an African scientific landscape with unique cultural, linguistic, and …

[HTML][HTML] No person left behind: Mapping the health policy landscape for genomics research in the Caribbean

J Bolleddula, D Simeon, SG Anderson… - The Lancet Regional …, 2022 - thelancet.com
The Caribbean has long been an under-represented geographical region in the field of
genomics research. Such under-representation may result in Caribbean people being …