Neutrophils are the most abundant circulating leukocytes in humans and the first immune
cells recruited at the site of inflammation. Classically perceived as short-lived effector cells …

Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …

The term “vasculitis” refers to a group of rare immune‐mediated diseases characterized by
the dysregulated immune system attacking blood vessels located in any organ of the body …

Antiphospholipid syndrome (APS) is a systemic autoimmune disease, where persistent
presence of antiphospholipid antibodies (aPL) leads to thrombotic and obstetric …

Rheumatoid arthritis (RA) is an autoimmune disease causing severe symptoms that are
difficult to treat. Nano-drug delivery system is recognized as a promising strategy for …

Introduction Neutrophils are the key cells of our innate immune system with a primary role in
host defense. They rapidly arrive at the site of infection and display a range of effector …

Sinomenine is an active substance extracted from the traditional Chinese medicine
Sinomenium acutum. Sinomenine has been shown to mediate a wide range of …

Background Significant changes in the epidemiology and natural history of rheumatoid
vasculitis (RV) have occurred with the introduction of biological therapies such as TNF …

Angiogenesis plays a key role in the pathological process of inflammation and invasion of
the synovium, and primarily drives the progression of rheumatoid arthritis (RA). Recent …

Neutrophils play critical roles in a broad spectrum of clinical conditions. Accordingly,
manipulation of neutrophil function may provide a powerful immunotherapeutic approach …