RNAi-based pest control: Production, application and the fate of dsRNA

L He, Y Huang, X Tang - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The limitations of conventional pesticides have raised the demand for innovative and
sustainable solutions for plant protection. RNA Interference (RNAi) triggered by dsRNA has …

Maximizing the potential of attractive targeted sugar baits (ATSBs) for integrated vector management

TM Njoroge, M Hamid-Adiamoh, M Duman-Scheel - Insects, 2023 - mdpi.com
Simple Summary Current mosquito control efforts are insufficient for preventing mosquito-
borne illnesses. Attractive targeted sugar bait (ATSB) technology is an emerging mosquito …

Pesticides and human health

R Shah - Emerging contaminants, 2020 - books.google.com
Pesticides are used in managing pests and their use will continue in future because of food
security and vector control. Most pesticides are potentially toxic to human beings resulting in …

Mosquito gene targeted RNAi studies for vector control

M Yadav, N Dahiya, N Sehrawat - Functional & Integrative Genomics, 2023 - Springer
Vector-borne diseases are serious public health concern. Mosquito is one of the major
vectors responsible for the transmission of a number of diseases like malaria, Zika …

Engineering strategies for insect viruses and microbes for dsRNA production and delivery to insects for targeted gene silencing

Q Xue, É Avila dos Santos, G Smagghe… - Entomologia …, 2023 - biblio.ugent.be
RNA interference (RNAi)-based pest control is viewed as a safe and effective method for
insect pest control. However, the stability and efficient cellular delivery of the double …

[HTML][HTML] New tools for Aedes control: mass trapping

R Barrera - Current opinion in insect science, 2022 - Elsevier
Aedes aegypti, the main vector of dengue, chikungunya, and Zika viruses uses artificial
containers around homes to undergo immature development, making household-level …

Characterization of a novel RNAi yeast insecticide that silences mosquito 5-HT1 receptor genes

K Mysore, TM Njoroge, ATM Stewart, N Winter… - Scientific Reports, 2023 - nature.com
G protein-coupled receptors (GPCRs), which regulate numerous intracellular signaling
cascades that mediate many essential physiological processes, are attractive yet …

A Broad-Based Mosquito Yeast Interfering RNA Pesticide Targeting Rbfox1 Represses Notch Signaling and Kills Both Larvae and Adult Mosquitoes

K Mysore, L Sun, LK Hapairai, CW Wang, JB Roethele… - Pathogens, 2021 - mdpi.com
Prevention of mosquito-borne infectious diseases will require new classes of
environmentally safe insecticides and novel mosquito control technologies. Saccharomyces …

Targeting Mosquitoes through Generation of an Insecticidal RNAi Yeast Strain Using Cas-CLOVER and Super PiggyBac Engineering in Saccharomyces cerevisiae

C Brizzee, K Mysore, TM Njoroge, S McConnell… - Journal of Fungi, 2023 - mdpi.com
The global deployment of RNAi yeast insecticides involves transitioning from the use of
laboratory yeast strains to more robust strains that are suitable for scaled fermentation. In …

A Yeast RNA-Interference Pesticide Targeting the Irx Gene Functions as a Broad-Based Mosquito Larvicide and Adulticide

K Mysore, L Sun, LK Hapairai, CW Wang, J Igiede… - Insects, 2021 - mdpi.com
Simple Summary It is critical that we identify new methods of preventing mosquito-borne
infectious diseases, which threaten millions of people worldwide. In this investigation, we …