A systematic review of interventions for children with cerebral palsy: state of the evidence

I Novak, S Mcintyre, C Morgan… - … medicine & child …, 2013 - Wiley Online Library
Aim The aim of this study was to describe systematically the best available intervention
evidence for children with cerebral palsy (CP). Method This study was a systematic review of …

Conversion Ratio between Botox®, Dysport®, and Xeomin® in Clinical Practice

F Scaglione - Toxins, 2016 - mdpi.com
Botulinum neurotoxin has revolutionized the treatment of spasticity and is now administered
worldwide. There are currently three leading botulinum neurotoxin type A products available …

Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increased in vivo sarcomere length

LR Smith, KS Lee, SR Ward… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary Muscle spasticity, due to an upper motoneuron lesion, often leads
to muscle contractures that limit range of motion and cause increased muscle stiffness …

Clinical applications of botulinum toxin

D Dressler - Current opinion in microbiology, 2012 - Elsevier
History The therapeutic use of BT was prepared during the late 1960s by Alan B. Scott from
the Smith-Kettlewell Eye Research Institute, San Francisco, CA, USA [67]. Searching for a …

Botulinum toxin assessment, intervention and after‐care for lower limb spasticity in children with cerebral palsy: international consensus statement

SC Love, I Novak, M Kentish… - European journal of …, 2010 - Wiley Online Library
Botulinum neurotoxin type‐A (BoNT‐A) has been used in association with other
interventions in the management of spasticity in children with cerebral palsy (CP) for almost …

Clinical assessment and management of spasticity: a review

T Rekand - Acta neurologica scandinavica, 2010 - Wiley Online Library
Rekand T. Clinical assessment and management of spasticity: a review. Acta Neurol Scand:
2010: 122 (Suppl. 190): 62–66.© 2010 John Wiley & Sons A/S. Spasticity is a sign of upper …

On muscle spindles, dystonia and botulinum toxin

RL Rosales, D Dressler - European journal of neurology, 2010 - Wiley Online Library
Dystonia may produce co‐contractions and constant strain in numerous muscle fibers,
including those of the muscle spindles. As proprioceptors, muscle spindles detect dynamic …

International consensus statement for the use of botulinum toxin treatment in adults and children with neurological impairments–introduction

A Esquenazi, I Novak, G Sheean… - European journal of …, 2010 - Wiley Online Library
Botulinum neurotoxin (BoNT) is most commonly used to reduce focal over‐activity in skeletal
muscle, although newer indications such as management of drooling, pain and tremor are …

The use of botulinum toxin A in children with cerebral palsy, with a focus on the lower limb

G Molenaers, A Van Campenhout… - Journal of children's …, 2010 - journals.sagepub.com
Purpose The purpose of this review is to clarify the role of botulinum toxin serotype A (BTX-
A) in the treatment of children with cerebral palsy (CP), with a special focus on the lower …

A systematic review: efficacy of botulinum toxin in walking and quality of life in post-stroke lower limb spasticity

AD Gupta, WH Chu, S Howell, S Chakraborty… - Systematic reviews, 2018 - Springer
Background Improved walking is one of the highest priorities in people living with stroke.
Post-stroke lower limb spasticity (PSLLS) impedes walking and quality of life (QOL). The …