Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

Esophageal cancer (EC) is frequently considered a lethal malignancy and is often identified
at a later stage. It is one of the major causes of cancer-related deaths globally. The …

Background Most studies of firefighter cancer risks were conducted prior to 1990 and do not
reflect risk from advances in building materials. Methods A case–control study using …

Barrett's oesophagus is a precursor of oesophageal adenocarcinoma. In this common
condition, squamous epithelium in the oesophagus is replaced by columnar epithelium in …

While the genomes of normal tissues undergo dynamic changes over time, little is
understood about the temporal-spatial dynamics of genomes in premalignant tissues that …

Many studies have provided observational data on the association of obesity and thyroid
cancers, but only few of them propose mechanisms that would permit a better understanding …

Cranberries are rich in bioactive constituents reported to influence a variety of health
benefits, ranging from improved immune function and decreased infections to reduced …

Background & Aims Inflammation in the gastrointestinal tract may lead to the development of
cancer. Dicarbonyl electrophiles, such as isolevuglandins (isoLGs), are generated from lipid …

Esophageal adenocarcinoma is the eighth most common malignancy worldwide. The
overall prognosis is poor, with 5-year survival ranges of approximately 15–25%, and 30 …

The human gastrointestinal tract is in constant contact with microbial stimuli. Its barriers have
to ensure co-existence with the commensal bacteria, while enabling surveillance of intruding …