Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

In recent years, an increasingly more in depth understanding of tumor metabolism in
tumorigenesis, tumor growth, metastasis, and prognosis has been achieved. The broad …

PURPOSE Mutations in the HRAS (m HRAS) proto-oncogene occur in 4%-8% of patients
with recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) …

Simple Summary Tumor infiltrating lymphocytes (TILs) have been demonstrated as
prognostic biomarkers in multiple cancer types. Among the various TIL phenotypic sub …

Head and neck cancers are a heterogeneous group of tumors that are highly aggressive
and collectively represent the sixth most common cancer worldwide. Ninety percent of head …

Head and neck squamous cell carcinoma (HNSCC) arises from the epithelial lining of the
oral cavity, hypopharynx, oropharynx, and larynx. There are several potential risk factors that …

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide, with
890,000 new cases and 450,000 deaths in 2018, and although the survival statistics for …

Many cancer therapies aim to trigger apoptosis in cancer cells. Nevertheless, the presence
of oncogenic alterations in these cells and distorted composition of tumour …

Background Despite recent advances in understanding the complex immunologic
dysfunction in the tumor microenvironment (TME), fewer than 20% of patients with head and …

Oral cancers constitute the majority of head and neck tumors, with a relatively high incidence
and poor survival rate in developing countries. While the five-year survival rates of the oral …