The role of short-chain fatty acids in microbiota–gut–brain communication

B Dalile, L Van Oudenhove, B Vervliet… - Nature reviews …, 2019 - nature.com
Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

[HTML][HTML] Diet and the microbiota–gut–brain axis: sowing the seeds of good mental health

K Berding, K Vlckova, W Marx, H Schellekens… - Advances in …, 2021 - Elsevier
Over the past decade, the gut microbiota has emerged as a key component in regulating
brain processes and behavior. Diet is one of the major factors involved in shaping the gut …

Implications of gut microbiota in neurodegenerative diseases

H Zhang, Y Chen, Z Wang, G Xie, M Liu… - Frontiers in …, 2022 - frontiersin.org
The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …

Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023 - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

Are the epigenetic changes predictive of therapeutic efficacy for psychiatric disorders? A translational approach towards novel drug targets

V Micale, M Di Bartolomeo, S Di Martino, T Stark… - Pharmacology & …, 2023 - Elsevier
The etiopathogenesis of mental disorders is not fully understood and accumulating evidence
support that clinical symptomatology cannot be assigned to a single gene mutation, but it …

How the epigenome integrates information and reshapes the synapse

RR Campbell, MA Wood - Nature Reviews Neuroscience, 2019 - nature.com
In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

Gut microbiota interaction with the central nervous system throughout life

J Ojeda, A Ávila, PM Vidal - Journal of Clinical Medicine, 2021 - mdpi.com
During the last years, accumulating evidence has suggested that the gut microbiota plays a
key role in the pathogenesis of neurodevelopmental and neurodegenerative diseases via …

[HTML][HTML] Microbiota and neurological disorders: a gut feeling

H MoosWalter, V FallerDouglas… - BioResearch open …, 2016 - liebertpub.com
In the past century, noncommunicable diseases have surpassed infectious diseases as the
principal cause of sickness and death, worldwide. Trillions of commensal microbes live in …

Gut microbiota as a therapeutic target to ameliorate the biochemical, neuroanatomical, and behavioral effects of traumatic brain injuries

MW Rice, JD Pandya, DA Shear - Frontiers in neurology, 2019 - frontiersin.org
Current efficacious treatments for traumatic brain injury (TBI) are lacking. Establishment of a
protective gut microbiota population offers a compelling therapeutic avenue, as brain injury …

[HTML][HTML] Swine gut microbiota and its interaction with host nutrient metabolism

H Wang, R Xu, H Zhang, Y Su, W Zhu - Animal Nutrition, 2020 - Elsevier
Gut microbiota is generally recognized to play a crucial role in maintaining host health and
metabolism. The correlation among gut microbiota, glycolipid metabolism, and metabolic …