[HTML][HTML] Accuracy of HPV E6/E7 oncoprotein tests to detect high-grade cervical lesions: a systematic literature review and meta-analysis

L Downham, I Jaafar, ML Rol, V Nyawira Nyaga… - British Journal of …, 2024 - nature.com
Background Cervical carcinogenesis is mediated by the HPV-E6 and E7 oncoproteins,
considered as biomarkers usable in managing screen-positive women. Methods We …

Cumulative risk of cervical intraepithelial neoplasia for women with normal cytology but positive for human papillomavirus: systematic review and meta‐analysis

T Malagon, KD Volesky, S Bouten… - … Journal of Cancer, 2020 - Wiley Online Library
Most women positive for human papillomavirus (HPV) are cytology normal. The optimal
screen‐management of these women is unclear given their risk of developing precancer …

Eight‐type human papillomavirus E6/E7 oncoprotein detection as a novel and promising triage strategy for managing HPV‐positive women

R Rezhake, SY Hu, S Zhao, XQ Xu… - … journal of cancer, 2019 - Wiley Online Library
The management of HPV‐positive women becomes particularly crucial in cervical cancer
screening. Here we assessed whether detection of E6 or E7 oncoproteins targeting eight …

Human papillomavirus viral load as a useful triage tool for non-16/18 high-risk human papillomavirus positive women: a prospective screening cohort study

L Dong, MZ Wang, X Zhao, R Feng, S Hu, Q Zhang… - Gynecologic …, 2018 - Elsevier
Objective ASCCP cervical cancer screening guidelines recommend triaging high-risk
human papillomavirus (hrHPV) positive women with cytology and genotyping, but cytology is …

[HTML][HTML] Risk stratification of HPV 16 DNA methylation combined with E6 oncoprotein in cervical cancer screening: a 10-year prospective cohort study

L Dong, L Zhang, SY Hu, RM Feng, XL Zhao… - Clinical …, 2020 - Springer
Background How to best triage human papillomavirus (HPV) positive women remains
controversial in an era of HPV primary screening of cervical cancer. Here, we assessed the …

Performance of an HPV 16/18 E6 oncoprotein test for detection of cervical precancer and cancer

A Ferrera, W Valladares, Y Cabrera… - … Journal of Cancer, 2019 - Wiley Online Library
HPV testing is a better alternative for cervical cancer screening, but additional procedures
are required for triage of HPV positive women. HPV encoded oncoproteins E6 and E7, as …

[HTML][HTML] Performance of human papillomavirus E6/E7 mRNA assay for primary cervical cancer screening and triage: population-based screening in China

J Zhang, D Yang, X Cui, G Liu, Z Cui… - Frontiers in Cellular …, 2022 - frontiersin.org
Objective Cervical cancer screening is very important in the prevention and treatment of
cervical cancer. In China, the cervical screening strategy needs to be improved. To explore a …

[HTML][HTML] Performance of OncoE6 cervical test with collection methods enabling self-sampling

A Krings, AM Dückelmann, L Moser, J Gollrad… - BMC Women's …, 2018 - Springer
Background The paradigm shift from cytological screening to Human Papillomavirus (HPV)-
based screening for cervical cancer allows the introduction of new technologies in sample …

Risk prediction of cervical cancer and precancers by type-specific human papillomavirus: evidence from a population-based cohort study in China

L Dong, SY Hu, Q Zhang, RM Feng, L Zhang… - Cancer Prevention …, 2017 - AACR
Risk stratification of human papillomavirus (HPV)-positive women is needed to avoid
excessive colposcopy and overtreatment in cervical cancer screening. We aimed to evaluate …

[HTML][HTML] Development of models for cervical cancer screening: construction in a cross-sectional population and validation in two screening cohorts in China

Z Wu, T Li, Y Han, M Jiang, Y Yu, H Xu, L Yu, J Cui… - BMC medicine, 2021 - Springer
Background Current methods for cervical cancer screening result in an increased number of
referrals and unnecessary diagnostic procedures. This study aimed to develop and evaluate …