The gut microbiota–brain axis in behaviour and brain disorders
LH Morais, HL Schreiber IV… - Nature Reviews …, 2021 - nature.com
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …
hosts to regulate the development and function of the immune, metabolic and nervous …
Macrophage cell membrane-based nanoparticles: a new promising biomimetic platform for targeted delivery and treatment
Y Wu, S Wan, S Yang, H Hu, C Zhang, J Lai… - Journal of …, 2022 - Springer
Synthetic nanoparticles with surface bioconjugation are promising platforms for targeted
therapy, but their simple biological functionalization is still a challenging task against the …
therapy, but their simple biological functionalization is still a challenging task against the …
[HTML][HTML] A human brain vascular atlas reveals diverse mediators of Alzheimer's risk
The human brain vasculature is of great medical importance: its dysfunction causes
disability and death, and the specialized structure it forms—the blood–brain barrier …
disability and death, and the specialized structure it forms—the blood–brain barrier …
The blood-brain barrier: Physiology and strategies for drug delivery
The blood-brain barrier (BBB) is a dynamic structure that functions as a gatekeeper,
reflecting the unique requirements of the brain. In this review, following a brief historical …
reflecting the unique requirements of the brain. In this review, following a brief historical …
Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches
K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …
therapy, currently, there is no significant progress in the treatment of different types of brain …
Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke
L Kang, H Yu, X Yang, Y Zhu, X Bai, R Wang… - Nature …, 2020 - nature.com
Neovascularization and vascular remodeling are functionally important for brain repair after
stroke. We show that neutrophils accumulate in the peri-infarct cortex during all stages of …
stroke. We show that neutrophils accumulate in the peri-infarct cortex during all stages of …
Absorption, distribution, and toxicity of per-and polyfluoroalkyl substances (PFAS) in the brain: a review
Per-and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals colloquially
known as “forever chemicals” because of their high persistence. PFAS have been detected …
known as “forever chemicals” because of their high persistence. PFAS have been detected …
Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection
W Abdullahi, D Tripathi… - American Journal of …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) is a physical and biochemical barrier that precisely controls
cerebral homeostasis. It also plays a central role in the regulation of blood-to-brain flux of …
cerebral homeostasis. It also plays a central role in the regulation of blood-to-brain flux of …
Overcoming blood–brain barrier transport: Advances in nanoparticle-based drug delivery strategies
The blood–brain barrier (BBB), a unique structure in the central nervous system (CNS),
protects the brain from bloodborne pathogens by its excellent barrier properties …
protects the brain from bloodborne pathogens by its excellent barrier properties …
The future of stem cell therapies for Parkinson disease
M Parmar, S Grealish, C Henchcliffe - Nature Reviews Neuroscience, 2020 - nature.com
Cell-replacement therapies have long been an attractive prospect for treating Parkinson
disease. However, the outcomes of fetal tissue-derived cell transplants in individuals with …
disease. However, the outcomes of fetal tissue-derived cell transplants in individuals with …