Synthesis and Antitubercular activity of new Thiazolidinones with Pyrazinyl and Thiazolyl scaffolds
ST Dhumal, AR Deshmukh, LD Khillare… - Journal of …, 2017 - Wiley Online Library
Emergence of multidrug resistant and extensively drug resistant tuberculosis has prompted
to develop new molecular entities to treat the disease. A series of new 4‐thiazolidinones …
to develop new molecular entities to treat the disease. A series of new 4‐thiazolidinones …
Synthesis and biological testing of (5Z)-2-aryl-5-arylmethylidene-3,5-dihydro-4H-imidazol-4-ones as antimitotic agents
AA Beloglazkina, B Wobith, ES Barskaia… - Medicinal Chemistry …, 2016 - Springer
Compounds interacting with cell protein tubulin and microtubules represent an important
type of antimitotic agents. A series of tubulin-targeted 2-aryl-4-benzoyl-imidazoles were …
type of antimitotic agents. A series of tubulin-targeted 2-aryl-4-benzoyl-imidazoles were …
Synthesis of new thiazole derivatives and evaluation of their antimicrobial and cytotoxic activities
Abstract Novel 2-heteroaryl-N-[4-(substituted aryl) thiazol-2-yl] propanamide derivatives (7a–
7o) were synthesized and investigated for their antimicrobial activity. Among the tested …
7o) were synthesized and investigated for their antimicrobial activity. Among the tested …
Synthesis, cytotoxic evaluation, and molecular docking study of 4, 5-diaryl-thiazole-2-thione analogs of combretastatin A-4 as microtubule-binding agents
A series of combretastatin A-4 analogs in which cis-olefinic bond replaced by thiazole ring
were prepared by reaction of α-bromo-1, 2-(p-substituted) diaryl-1-ethanones and …
were prepared by reaction of α-bromo-1, 2-(p-substituted) diaryl-1-ethanones and …
Synthesis, Characterization, and Molecular Docking of Novel bis‐thiazolyl Thienothiophene Derivatives as Promising Cytotoxic Antitumor Drug
SM Gomha, MA El‐Hashash… - Journal of …, 2017 - Wiley Online Library
A novel, facile reaction for the synthesis of series of bis‐thiazole derivatives has been
developed from the reaction of the appropriate thiosemicarbazone derivatives and bis‐2 …
developed from the reaction of the appropriate thiosemicarbazone derivatives and bis‐2 …
Iodine and DMSO as Surrogate of Hazardous Metal and Non‐Metal Reagents in Organic Synthesis
R Reetu, S Kalita, S Dash, CC Malakar - ChemistrySelect, 2024 - Wiley Online Library
Organic synthesis involves the production of important chemical structures using scalable
and cost‐effective methods that are also environmentally friendly. In this review, a detailed …
and cost‐effective methods that are also environmentally friendly. In this review, a detailed …
An efficient method for the synthesis of 2-thiazoleacetic acid N-sulfonyl amidines
VG Il'kin, VS Berseneva, PА Slepukhin… - Chemistry of Heterocyclic …, 2018 - Springer
A three-step method was designed and developed on the basis of retrosynthetic analysis for
the synthesis of hybrid molecules containing a thiazole ring and an N-sulfonyl amidine …
the synthesis of hybrid molecules containing a thiazole ring and an N-sulfonyl amidine …
One-pot multicomponent synthesis of novel 1-thiazolyl-5-coumarin-3-yl-pyrazole derivatives and evaluation of their cytotoxic activity
R Velpula, R Deshineni, R Gali, R Bavantula - Research on Chemical …, 2016 - Springer
A series of novel 1-thiazolyl-5-coumarin-3-yl-pyrazole derivatives (4a–l) were synthesized
via one-pot multicomponent reaction of 5-substituted salicylaldehydes (1a–c), 4-hydroxy-6 …
via one-pot multicomponent reaction of 5-substituted salicylaldehydes (1a–c), 4-hydroxy-6 …
A simple, three-component synthesis of 2-aminothiazoles using trimethylsilyl isothiocyanate
V Golubev, F Zubkov, M Krasavin - Tetrahedron Letters, 2013 - Elsevier
A simple, three-component synthesis of 2-aminothiazoles using trimethylsilyl isothiocyanate -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …
Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors
G Rubbini, AB Buades-Martín… - Future Medicinal …, 2018 - Future Science
Aim: Choline kinase α inhibitors represent one of the newest classes of cytotoxic drugs for
cancer treatment, since aberrant choline metabolism is a characteristic shared by many …
cancer treatment, since aberrant choline metabolism is a characteristic shared by many …