Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals

N Trevijano-Contador, HC de Oliveira… - PLoS …, 2018 - journals.plos.org
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of
the cells during infection. In particular, this process can occur by enlarging the size of the …

Current insight into the role of mRNA decay pathways in fungal pathogenesis

Z Firdous, S Kalra, R Chattopadhyay, VK Bari - Microbiological Research, 2024 - Elsevier
Pathogenic fungal species can cause superficial and mucosal surface infections, to
potentially fatal systemic or invasive infections in humans. These infections are more …

The RNAi mechanism regulates a new exonuclease gene involved in the virulence of Mucorales

C Pérez-Arques, MI Navarro-Mendoza… - International Journal of …, 2021 - mdpi.com
Mucormycosis is a lethal disease caused by Mucorales, which are emerging as human
causes that explain the high mortality for this disease. Consequently, the research …

Control of mRNA stability in fungi by NMD, EJC and CBC factors through 3′ UTR introns

Y Zhang, MS Sachs - Genetics, 2015 - academic.oup.com
In higher eukaryotes the accelerated degradation of mRNAs harboring premature
termination codons is controlled by nonsense-mediated mRNA decay (NMD), exon junction …

Role of Cln1 during melanization of Cryptococcus neoformans

R García-Rodas, N Trevijano-Contador… - Frontiers in …, 2015 - frontiersin.org
Cryptococcus neoformans is an opportunistic fungal pathogen that has several well-
described virulence determinants. A polysaccharide capsule and the ability to produce …

A spontaneous mutation in DNA polymerase POL3 during in vitro passaging causes a hypermutator phenotype in Cryptococcus species

KJ Boyce, C Cao, C Xue, A Idnurm - DNA repair, 2020 - Elsevier
Passaging of microbes in vitro can lead to the selection of microevolved derivatives with
differing properties to their original parent strains. One well characterised instance is the …

The influence of the mating type on virulence of Mucor irregularis

W Xu, G Liang, J Peng, Z Long, D Li, M Fu, Q Wang… - Scientific Reports, 2017 - nature.com
Mucor irregularis is an emerging fungal pathogen that cause cutaneous infection and could
cause death. However, little is known about its mechanism of pathogenesis. There is …

Identification of a basidiomycete-specific Vilse-like GTPase activating proteins (GAPs) and its roles in the production of virulence factors in Cryptococcus neoformans

K Rahim, L Huo, C Li, P Zhang, A Basit… - FEMS Yeast …, 2017 - academic.oup.com
Cryptococcus neoformans is a basidiomycetous pathogenic yeast that causes fatal
infections in both immunocompetent and immunocompromised patients. Regulation on the …

Effects of 5′-3′ Exonuclease Xrn1 on Cell Size, Proliferation and Division, and mRNA Levels of Periodic Genes in Cryptococcus neoformans

X Zhao, X Li, P Zhang, C Li, W Feng, X Zhu, D Wei - Genes, 2020 - mdpi.com
Cell size affects almost all biosynthetic processes by controlling the size of organelles and
disrupting the nutrient uptake process. Yeast cells must reach a critical size to be able to …

Cryptococcus neoformans can form titan-like cells in vitro in response to multiple signals that require the activation of several transduction pathways

N Trevijano-Contador, SA Rossi, HC de Oliveira… - BioRXiv, 2017 - biorxiv.org
Cryptococcus neoformans is an encapsulated pathogenic yeast that can change the size of
the cells during infection. In particular, this process can occur by enlarging the size of the …