Assessing insulin sensitivity and resistance in syndromes of severe short stature

J Guevara-Aguirre, E Teran, D Lescano… - Growth Hormone & IGF …, 2020 - Elsevier
Individuals affected with two genetic syndromes identified in Ecuador have severe short
stature and diminished insulin secretion, along with essentially different GH …

Exploring the relationship between vitamin D and leptin hormones in type 2 diabetes mellitus patients from Kuwait

F Lari, T Alabduljaleel, O Mojiminiyi… - … Molecular Biology and …, 2022 - degruyter.com
Background Type 2 diabetes mellitus (T2DM) and obesity are prevalent in Kuwait. Vitamin D
(VD) deficiency and leptin resistance are risk factors for both disorders. A correlation …

[PDF][PDF] High-fat diet with stress impaired islets' insulin secretion by reducing plasma estradiol and pancreatic GLUT2 protein levels in rats' proestrus phase

M Salimi, H Zardooz, F Khodagholi… - J Physiol …, 2016 - researchgate.net
This study was conducted to determine whether two estrus phases (proestrus and diestrus)
in female rats may influence the metabolic response to a high-fat diet and/or stress, focusing …

Leptin in non PCOS and PCOS women: a comparative study.

SJ Ramanand, JB Ramanand, SS Jain, GT Raparti… - 2014 - pesquisa.bvsalud.org
Background: Leptin, a hormone secreted by adipose tissues, controls body weight through
regulation of appetite and thermogenesis. The present study was aimed to observe role of …

miR-876-3p regulates glucose homeostasis and insulin sensitivity by targeting adiponectin

S Rajan, G Panzade, A Srivastava… - Journal of …, 2018 - joe.bioscientifica.com
miRNA have been known to regulate diverse cellular and molecular functions. In the earlier
study, we have reported that adipocytes differentiated from human mesenchymal stem cells …

[HTML][HTML] Effect of methanolic extract of Phyllanthus niruri on leptin level in animal model of diabetes Mellitus

A Kumar, AK Rana, A Singh… - Biomedical and …, 2019 - biomedpharmajournal.org
To study the effect of methanolic extract of Phyllanthus niruri on animal model of Diabetes
Mellitus. Diabetes Mellitus was induced in rats by injecting Streptozotocin (60mg/kg) …

[HTML][HTML] Correlation of Leptin in Patients With Type 2 Diabetes Mellitus

K Manglani, NN Anika, D Patel, S Jhaveri, C Avanthika… - Cureus, 2024 - ncbi.nlm.nih.gov
The exponential increase in diabetes mellitus (DM) poses serious public health concerns. In
this review, we focus on the role of leptin in type 2 DM. The peripheral actions of leptin …

Multi-omics analysis identifies rare variation in leptin/PPAR gene sets and hypermethylation of ABCG1 contribute to antipsychotics-induced metabolic syndromes

W Zhou, J Sun, C Huai, Y Liu, L Chen, Z Yi, Q Lv… - Molecular …, 2022 - nature.com
Antipsychotic-induced metabolic syndrome (APs-induced Mets) is the most common
adverse drug reaction, which affects more than 60% of the psychiatric patients. Although the …

Obesity and cancer

F Cmrečak, I Andrašek, V Gregov… - … : Croatian Journal of …, 2020 - hrcak.srce.hr
Sažetak For the past several decades, we have witnessed the emergence of the obesity
pandemic worldwide and, simultaneously, the increase of incidence of malignant diseases …

[PDF][PDF] Combinatorial effect of leptin, tumor necrosis factor-αlpha, and vitamin D in progression of type 2 diabetes in Kashmiri population

I Din, S Majid, F Rashid, I Hussain, RK Koul… - Asian J Pharm Clin …, 2018 - researchgate.net
Objectives: Type 2 diabetes mellitus (T2DM) is a metabolic disorder usually characterized by
hyperglycemia. Adipose tissue secretes bioactive substances known as adipocytokines …