[HTML][HTML] Emerging vaccine nanotechnology: from defense against infection to sniping cancer

C Feng, Y Li, BE Ferdows, DN Patel, J Ouyang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Looking retrospectively at the development of humanity, vaccination is an unprecedented
medical landmark that saves lives by harnessing the human immune system. During the …

Amphiphilic self-assembly peptides: Rational strategies to design and delivery for drugs in biomedical applications

C Zhao, H Chen, F Wang, X Zhang - Colloids and Surfaces B: Biointerfaces, 2021 - Elsevier
Amphiphilic self-assembling peptides are widely used in tissue and cell engineering,
antimicrobials, drug-delivery systems and other biomedical fields due to their good …

Chiral supramolecular nanomaterials: From chirality transfer and amplification to regulation and applications

W Chen, B Li, G Gao, T Sun - Interdisciplinary Materials, 2023 - Wiley Online Library
Chirality is an omnipresent structural feature found in nature. The transfer and amplification
of chirality are widely recognized phenomena. In appropriate solvents, chiral molecules can …

Bio-inspired drug delivery systems: From synthetic polypeptide vesicles to outer membrane vesicles

Y Zhang, Y Lu, Y Xu, Z Zhou, Y Li, W Ling, W Song - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a broad field that focuses on the development of nanocarriers to deliver
specific drugs to targeted sites. A synthetic polypeptide is a kind of biomaterial composed of …

The influence of component structural arrangement on peptide vaccine immunogenicity

N Alharbi, M Skwarczynski, I Toth - Biotechnology Advances, 2022 - Elsevier
Peptide-based subunit vaccines utilise minimal immunogenic components (ie peptides) to
generate highly specific immune responses, without triggering adverse reactions. However …

Cancer vaccines: from the state of the art to the most promising frontiers in the treatment of colorectal cancer

E Martinis, C Ricci, C Trevisan, G Tomadini, S Tonon - Pharmaceutics, 2023 - mdpi.com
Colorectal cancer represents 10% of all new cancer cases each year and accounts for
almost 10% of all cancer deaths. According to the WHO, by 2040 there will be a 60 …

Antiviral fibrils of self-assembled peptides with tunable compositions

J Dodd-o, A Roy, Z Siddiqui, R Jafari, F Coppola… - Nature …, 2024 - nature.com
The lasting threat of viral pandemics necessitates the development of tailorable first-
response antivirals with specific but adaptive architectures for treatment of novel viral …

Self-assembling peptides and carbon nanomaterials join forces for innovative biomedical applications

P Rozhin, C Charitidis, S Marchesan - Molecules, 2021 - mdpi.com
Self-assembling peptides and carbon nanomaterials have attracted great interest for their
respective potential to bring innovation in the biomedical field. Combination of these two …

Dendritic cell hybrid nanovaccine for mild heat inspired cancer immunotherapy

C Shi, C Jian, L Wang, C Gao, T Yang, Z Fu… - Journal of …, 2023 - Springer
Cancer therapeutic vaccine can induce antigen-specific immune response, which has
shown great potential in cancer immunotherapy. As the key factor of vaccine, antigen plays a …

Resolving the Nanoscale Structure of β-Sheet Peptide Self-Assemblies Using Single-Molecule Orientation–Localization Microscopy

W Zhou, CL O'Neill, T Ding, O Zhang, JS Rudra… - ACS …, 2024 - ACS Publications
Synthetic peptides that self-assemble into cross-β fibrils are versatile building blocks for
engineered biomaterials due to their modularity and biocompatibility, but their structural and …