[HTML][HTML] Linear epitope mapping in the E and NS1 proteins of dengue and Zika viruses: Prospection of peptides for vaccines and diagnostics

VH Aquino, MJ Fumagalli, A Silva… - Plos one, 2023 - journals.plos.org
The arrival of the Zika virus (ZIKV) in dengue virus (DENV)-endemic areas has posed
challenges for both differential diagnosis and vaccine development. Peptides have shown …

[HTML][HTML] Protective Efficacy Induced by the Common Eimeria Antigen Elongation Factor 2 against Challenge with Three Eimeria Species in Chickens

Y Mi, W Ding, L Xu, M Lu, R Yan, X Li, X Song - Vaccines, 2023 - mdpi.com
Avian coccidiosis arises from co-infection involving multiple Eimeria species, which could
give rise to substantial economic losses in the global poultry industry. As a result, multivalent …

Transcutaneous Immunization of 1D Rod-Like Tobacco-Mosaic-Virus-Based Peptide Vaccine via Tip-Loaded Dissolving Microneedles

J Ou, M Xing, G Lu, C Wan, K Li, W Jiang, W Qian… - Nano Letters, 2024 - ACS Publications
Peptide vaccines induce specific neutralizing antibodies and are effective in disease
prevention and treatment. However, peptide antigens have a low immunogenicity and are …

[HTML][HTML] Amyloidogenic propensity of self-assembling peptides and their adjuvant potential for use as DNA vaccines

PC Shrimali, S Chen, A Das, R Dreher, MK Howard… - Acta Biomaterialia, 2023 - Elsevier
De novo designed peptides that self-assemble into cross-β rich fibrillar biomaterials have
been pursued as an innovative platform for the development of adjuvant-and inflammation …

Drug Encapsulation via Peptide‐Based Polyelectrolyte Complexes

S Tabandeh, T Ateeq, L Leon - ChemBioChem, 2024 - Wiley Online Library
Peptide‐based polyelectrolyte complexes are biocompatible materials that can encapsulate
molecules with different polarities due to their ability to be precisely designed. Here we use …

[HTML][HTML] Nanomaterials-based vaccines to target intracellular bacterial pathogens

MA Files, KM Kristjansson, JS Rudra… - Frontiers in …, 2022 - frontiersin.org
Development of novel immunization approaches to combat a growing list of emerging and
ancient infectious agents is a global health priority. Intensive efforts over the last several …

DENV Peptides Delivered as Spherical Nucleic Acid Constructs Enhance Antigen Presentation and Immunogenicity in vitro and in vivo

J Zhao, J He, X Ding, Y Zhou, M Liu… - International Journal …, 2024 - Taylor & Francis
Background The global prevalence of Dengue virus (DENV) infection poses a significant
health risk, urging the need for effective vaccinations. Peptide vaccines, known for their …

Synthetic Multicomponent Nanovaccines Based on the Molecular Co-assembly of β-Peptides Protect against Influenza A Virus

S Bricha, M Côté-Cyr, T Tremblay… - ACS Infectious …, 2023 - ACS Publications
Peptides with the ability to self-assemble into nanoparticles have emerged as an attractive
strategy to design antigen delivery platforms for subunit vaccines. While toll-like receptor …

Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune …

Y Zhao, W Xiao, Y Wu, W Fan, L Li, C Yue… - The Journal of …, 2023 - journals.aai.org
Influenza A viruses (IAVs) and influenza B viruses (IBVs) cause annual epidemics in human
populations with seasonal circulation spikes. Peptide AM58− 66GL9 located at residues 58 …

Electrochemical aptasensor based on RGO/PPy/Au* NPs for diagnostic biosensing of SARS-CoV-2 in clinical samples: Experimental and molecular dynamics …

AM Jamshid, J Arjomandi, H Shi, S Shuang - Synthetic Metals, 2024 - Elsevier
A highly sensitive and selective E-DNA biosensor was fabricated on a gold substrate using a
reduced graphene oxide/polypyrrole/gold nanoparticle/oligonucleotide (RGO/PPy/Au …