Tendons are dense connective tissues with a hierarchical polarized structure that respond to
and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion …

Tendon injuries often result in significant pain and disability and impose severe clinical and
financial burdens on our society. Despite considerable achievements in the field of …

Tendinopathy is a multi-faceted pathology characterized by alterations in tendon
microstructure, cellularity and collagen composition. Challenged by the possibility of …

Tissue engineering (TE) has become a primary research topic for the treatment of diseased
or damaged tendon/ligament (T/L) tissue. T/L injuries pose a severe clinical burden …

Tendon disorders represent a very common pathology in today's population, and
tendinopathies that account 30% of tendon-related injuries, affect yearly millions of people …

Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided
into two types, chronic and acute. Each type of injury or degeneration can cause substantial …

The development of tendon-biomimetic nanofibrous scaffolds with mesenchymal stem cells
may represent a promising strategy to improve the unsatisfactory outcomes of traditional …

Despite all the efforts made in tissue engineering for tendon repair, the management of
tendon injuries still poses a challenge, as current treatments are unable to restore the …

Tendon aging is associated with an increasing prevalence of tendon injuries and/or chronic
tendon diseases, such as tendinopathy, which affects approximately 25% of the adult …

To recreate the in vivo niche for tendon tissue engineering in vitro, the characteristics of
tendon tissue underlines the use of biochemical and biophysical cues during tenocyte …