The human long non-coding RNA LINC00941 and its modes of action in health and disease

E Morgenstern, M Kretz - Biological Chemistry, 2023 - degruyter.com
Long non-coding RNAs have gained attention in recent years as they were shown to play
crucial roles in the regulation of cellular processes, but the understanding of the exact …

Crosstalk between lncRNAs and miRNAs in gastrointestinal cancer drug resistance

N Raei, R Safaralizadeh, M Hesseinpourfeizi… - Life sciences, 2021 - Elsevier
Gastrointestinal cancers are one of the most prevalent malignancies worldwide.
Dysregulation of lncRNAs by epigenetic alteration is crucial in gastrointestinal …

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2

J Wang, Z He, X Liu, J Xu, X Jiang, G Quan… - Cell death & …, 2022 - nature.com
Recently, long non-coding RNAs (lncRNA) have been proven to regulate pancreatic cancer
(PC) progression. We aimed to explore the pathogenesis of LINC00941 in PC regarding …

Reciprocal regulation of LINC00941 and SOX2 promotes progression of esophageal squamous cell carcinoma

JT Lu, ZY Yan, TX Xu, F Zhao, L Liu, F Li, W Guo - Cell death & disease, 2023 - nature.com
LINC00941 is a novel long noncoding RNA (lncRNA) and emerging as an important factor in
cancer development. However, the exact function and relative regulatory mechanism of …

lncHUB2: aggregated and inferred knowledge about human and mouse lncRNAs

GB Marino, ML Wojciechowicz, DJB Clarke… - Database, 2023 - academic.oup.com
Long non-coding ribonucleic acids (lncRNAs) account for the largest group of non-coding
RNAs. However, knowledge about their function and regulation is limited. lncHUB2 is a web …

Novel lncRNA panel as for prognosis in esophageal squamous cell carcinoma based on ceRNA network mechanism

J Zhang, F Xiao, G Qiang, Z Zhang… - … Methods in Medicine, 2021 - Wiley Online Library
Background. The competitive endogenous RNA (ceRNA) mechanism has been discovered
recently and regulating cancer‐related gene expressions. The ceRNA network participates …

A pleiotropic role of long non-coding RNAs in the modulation of Wnt/β-catenin and PI3K/Akt/mTOR signaling pathways in esophageal squamous cell carcinoma …

U Sharma, M Murmu, TS Barwal, HS Tuli, M Jain… - Current …, 2022 - mdpi.com
Despite the availability of modern techniques for the treatment of esophageal squamous cell
carcinoma (ESCC), tumor recurrence and metastasis are significant challenges in clinical …

miR-877-3p as a potential tumour suppressor of oesophageal squamous cell carcinoma

T Fukuda, H Baba, T Okumura, M Kanda… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: MicroRNAs (miRNAs) are abnormally expressed and involved in the
pathogenesis of various carcinomas. The present study aimed to identify novel miRNA …

Identification and validation of apparent imbalanced epi-lncRNAs prognostic model based on multi-omics data in pancreatic cancer

M Ke - Frontiers in molecular biosciences, 2022 - frontiersin.org
Background: Globally, pancreatic adenocarcinoma is a recognized cause of pancreatic
death (PAAD) associated with high mortality. Long non-coding RNAs (lncRNAs) play an …

Splice and dice: intronic microRNAs, splicing and cancer

ACH Wong, JEJ Rasko - Biomedicines, 2021 - mdpi.com
Introns span only a quarter of the human genome, yet they host around 60% of all known
microRNAs. Emerging evidence indicates the adaptive advantage of microRNAs residing …