Bone marrow–and adult kidney–derived stem/progenitor cells hold promise in the
development of therapies for renal failure. Here is reported the identification and …

Pluripotency is a unique biological state that allows cells to differentiate into any tissue type.
Here we describe a candidate pluripotency factor, Ronin, that possesses a THAP domain …

Renal failure has a high prevalence and is becoming a public health problem worldwide.
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …

The renal proximal tubule is a main target for drug-induced toxicity. The prediction of
proximal tubular toxicity during drug development remains difficult. Any in vitro methods …

Bisphenol S (BPS) is present in multitudinous consumer products and detected in both food
and water. It also has been a main substitute for bisphenol A (BPA) in the food-packaging …

Human amniotic fluid cells have been used as a diagnostic tool for the prenatal diagnosis of
fetal genetic anomalies for more than 50 years. Evidence provided in the last 5 years …

We investigated the proliferative capacity of renal proximal tubular cells in healthy rats.
Previously, we observed that tubular cells originate from differentiated cells. We now found …

Despite the enthusiasm for bioengineering of functional renal tissues for transplantation,
many obstacles remain before the potential of this technology can be realized in a clinical …

Acute kidney injury (AKI) is a common clinical problem and is associated with high mortality
rates. It is accepted that after AKI cellular regeneration of the proximal tubule occurs from …

The cancer stem cell (CSC) model has recently been approached also in renal cell
carcinoma (RCC). A few populations of putative renal tumor-initiating cells (TICs) were …