Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications

G Hajishengallis - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

Viruses, periodontitis, and comorbidities

F Teles, RG Collman, D Mominkhan… - Periodontology …, 2022 - Wiley Online Library
Seminal studies published in the 1990s and 2000s explored connections between
periodontal diseases and systemic conditions, revealing potential contributions of …

NIR responsive nitric oxide nanogenerator for enhanced biofilm eradication and inflammation immunotherapy against periodontal diseases

M Qi, X Ren, W Li, Y Sun, X Sun, C Li, S Yu, L Xu… - Nano Today, 2022 - Elsevier
Periodontal disease is one of the most common oral infectious diseases and closely related
to many systemic diseases which is in urgent need of novel and effective drugs. In particular …

Periodontal pockets: A potential reservoir for SARS-CoV-2?

Z Badran, A Gaudin, X Struillou, G Amador… - Medical hypotheses, 2020 - Elsevier
Periodontal pockets are the major clinical manifestation of Periodontitis, a chronic
inflammatory oral disease affecting the teeth-supporting tissues and has high prevalence in …

Potential implications of SARS-CoV-2 oral infection in the host microbiota

Z Xiang, H Koo, Q Chen, X Zhou, Y Liu… - Journal of Oral …, 2021 - Taylor & Francis
The oral cavity, as the entry point to the body, may play a critical role in the pathogenesis of
SARS-CoV-2 infection that has caused a global outbreak of the coronavirus disease 2019 …

[HTML][HTML] Periodontal inflammation-triggered by periodontal ligament stem cell pyroptosis exacerbates periodontitis

Q Chen, X Liu, D Wang, J Zheng, L Chen… - Frontiers in cell and …, 2021 - frontiersin.org
Periodontitis is an immune inflammatory disease that leads to progressive destruction of
bone and connective tissue, accompanied by the dysfunction and even loss of periodontal …

Alzheimer disease and the periodontal patient: New insights, connections, and therapies

MI Ryder, P Xenoudi - Periodontology 2000, 2021 - Wiley Online Library
Loss of cognitive function in the aging population, particular those with Alzheimer disease,
presents unique challenges to health practitioners. For the dental practitioner these include …

The human oral virome: shedding light on the dark matter

A Martínez, R Kuraji, YL Kapila - Periodontology 2000, 2021 - Wiley Online Library
Mediators of the initiation, development, and recurrence of periodontitis include the oral
microbiome embedded in subgingival plaque and the host immune response to a dysbiosis …

Primer on etiology and treatment of progressive/severe periodontitis: A systemic health perspective

J Slots - Periodontology 2000, 2020 - Wiley Online Library
Periodontology is an infectious disease‐based discipline. The etiopathology of
progressive/severe periodontitis includes active herpesviruses, specific bacterial pathogens …

The human oral phageome

SP Szafrański, J Slots, M Stiesch - Periodontology 2000, 2021 - Wiley Online Library
Oral bacteriophages (or phages), especially periodontal ones, constitute a growing area of
interest, but research on oral phages is still in its infancy. Phages are bacterial viruses that …