Validation of biomarkers of aging
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …
Biomarkers of aging for the identification and evaluation of longevity interventions
With the rapid expansion of aging biology research, the identification and evaluation of
longevity interventions in humans have become key goals of this field. Biomarkers of aging …
longevity interventions in humans have become key goals of this field. Biomarkers of aging …
From biological aging to functional decline: A narrative review of insights into chronic inflammation and intrinsic capacity
X Li, L Ma - Ageing Research Reviews, 2023 - Elsevier
Intrinsic capacity is the sum of an individual's physical and mental capacities, which helps
determine functional ability. Intrinsic capacity decline is an important predictor of adverse …
determine functional ability. Intrinsic capacity decline is an important predictor of adverse …
Association between aging-related biomarkers and longitudinal trajectories of intrinsic capacity in older adults
Intrinsic capacity (IC), the composite of physical and mental capacities, declines with age at
different rates and patterns between individuals. We aimed to investigate the association …
different rates and patterns between individuals. We aimed to investigate the association …
Reference centiles for intrinsic capacity throughout adulthood and their association with clinical outcomes: a cross-sectional analysis from the INSPIRE-T cohort
WH Lu, Y Rolland, S Guyonnet, P de Souto Barreto… - Nature Aging, 2023 - nature.com
Intrinsic capacity (IC), a function-centered construct, is defined as the composite of all
physical and mental capacities of an individual. IC and surrounding environmental factors …
physical and mental capacities of an individual. IC and surrounding environmental factors …
Subjective age and the association with intrinsic capacity, functional ability, and health among older adults in Norway
This study investigates the relationships between subjective age, intrinsic capacity,
functional ability and health among Norwegians aged 60 years and older. The Norwegian …
functional ability and health among Norwegians aged 60 years and older. The Norwegian …
Measures of attributes of locomotor capacity in older people: a systematic literature review following the COSMIN methodology
Background Locomotor capacity (LC) is an important domain of intrinsic capacity and key
determinant of functional ability and well-being in older age. The United Nations Decade of …
determinant of functional ability and well-being in older age. The United Nations Decade of …
Associations between vitality/nutrition and the other domains of intrinsic capacity based on data from the INSPIRE ICOPE-Care Program
L Gaussens, E González-Bautista, M Bonnefoy… - Nutrients, 2023 - mdpi.com
Background: The vitality domain of intrinsic capacity (IC) represents the synthesis of
biological interactions and metabolism. As part of the Integrated Care for Older People …
biological interactions and metabolism. As part of the Integrated Care for Older People …
[HTML][HTML] Association between intrinsic capacity and sarcopenia in hospitalized older patients
L Zhu, X Zong, X Shi, X Ouyang - The Journal of nutrition, health and aging, 2023 - Elsevier
Objectives This study aimed to clarify the association between intrinsic capacity (IC) and
sarcopenia in hospitalized older patients. Design A cross-sectional study. Setting Hospital …
sarcopenia in hospitalized older patients. Design A cross-sectional study. Setting Hospital …
Measurement properties of instruments to measure the fatigue domain of vitality capacity in community-dwelling older people: an umbrella review of systematic …
V Knoop, E Mathot, F Louter, D Beckwee… - Age and …, 2023 - academic.oup.com
Background Vitality capacity (VC) is a key domain of intrinsic capacity (IC) and is the
underlying biophysiological aspect of IC. Energy and metabolism (E&M) is one of the …
underlying biophysiological aspect of IC. Energy and metabolism (E&M) is one of the …