[HTML][HTML] Reprogramming of mesothelial-mesenchymal transition in chronic peritoneal diseases by estrogen receptor modulation and TGF-β1 inhibition

RB Wilson, R Archid, MA Reymond - International Journal of Molecular …, 2020 - mdpi.com
In chronic peritoneal diseases, mesothelial-mesenchymal transition is determined by cues
from the extracellular environment rather than just the cellular genome. The transformation …

Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly (ethylene glycol) hydrogels

LD Amer, LS Saleh, C Walker, S Thomas, WJ Janssen… - Acta biomaterialia, 2019 - Elsevier
Synthetic hydrogels, such as poly (ethylene glycol)(PEG), are promising for a range of in
vivo applications. However, like all non-biological biomaterials, synthetic hydrogels …

NLRP3 inflammasomes are involved in the progression of postoperative cognitive dysfunction: from mechanism to treatment

S Zhao, F Chen, D Wang, W Han, Y Zhang, Q Yin - Neurosurgical review, 2021 - Springer
Postoperative cognitive dysfunction (POCD) involves patient memory and learning decline
after surgery. POCD not only presents challenges for postoperative nursing and recovery but …

Extracellular cardiolipin regulates select immune functions of microglia and microglia-like cells

CB Pointer, TJ Wenzel, A Klegeris - Brain research bulletin, 2019 - Elsevier
Cardiolipin is a mitochondrial membrane phospholipid with several well-defined metabolic
roles. Cardiolipin can be released extracellularly by damaged cells and has been shown to …

Reinterpreting renal hemodynamics: the importance of venous congestion and effective organ perfusion in acute kidney injury

C Kopitko, T Gondos, T Fülöp, L Medve - The American journal of the …, 2020 - Elsevier
The significance of effective renal perfusion is relatively underemphasized in the current
literature. From a renal standpoint, besides optimizing cardiac output, renal perfusion should …

[HTML][HTML] Obesity paradox, obesity orthodox, and the metabolic syndrome: an approach to unity

J Roth, N Sahota, P Patel, SF Mehdi, MM Wiese… - Molecular …, 2016 - Springer
Obesity and its accompanying metabolic syndrome are strongly associated with heightened
morbidity and mortality in older adults. In our review of more than 20 epidemiologic studies …

[HTML][HTML] Danger signals in regulating the immune response to solid organ transplantation

JL Todd, SM Palmer - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Endogenous danger signals, or damage-associated molecular patterns (DAMPs), are
generated in response to cell stress and activate innate immunity to provide a pivotal …

Intrinsic cancer vaccination

Y Yang, GH Nam, GB Kim, YK Kim, IS Kim - Advanced Drug Delivery …, 2019 - Elsevier
Immunotherapy is revolutionizing the treatment of cancer, and the current
immunotherapeutics have remarkably improved the outcomes for some cancer patients …

2019 ATVB Plenary Lecture: Interleukin-2 Therapy in Cardiovascular Disease: The Potential to Regulate Innate and Adaptive Immunity

TX Zhao, SA Newland, Z Mallat - Arteriosclerosis, Thrombosis, and …, 2020 - Am Heart Assoc
Regulatory T cells and type-2 innate lymphoid cells represent 2 subsets of immune cells,
which have been shown in preclinical models to be important in atherosclerosis and …

[HTML][HTML] Issues and consequences of using nutrition to modulate the avian immune response

MH Kogut - Journal of Applied Poultry Research, 2017 - Elsevier
Combatting antimicrobial-resistant bacteria is a high priority for both public health and
agriculture in the United States and globally. Antibiotic use in animals and humans is …