Prospective de novo drug design with deep interactome learning

K Atz, L Cotos, C Isert, M Håkansson, D Focht… - Nature …, 2024 - nature.com
De novo drug design aims to generate molecules from scratch that possess specific
chemical and pharmacological properties. We present a computational approach utilizing …

[HTML][HTML] Novel players in the development of chemoresistance in ovarian cancer: ovarian cancer stem cells, non-coding RNA and nuclear receptors

S Alam, PK Giri - Cancer Drug Resistance, 2024 - ncbi.nlm.nih.gov
Ovarian cancer (OC) ranks as the fifth leading factor for female mortality globally, with a
substantial burden of new cases and mortality recorded annually. Survival rates vary …

The Effect of Eight Weeks of High-Intensity Interval Training on Follistatin Gene Expression in the Fast and Slow Twitch Muscles of Rats with Myocardial Infarction

E Ramezani, M Ghahramani, H Ghaedi - Iranian Journal of Medical …, 2024 - ijms.sums.ac.ir
Background: Myocardial infarction causes mitochondrial atrophy and loss of function by
reducing mitochondrial volume. Therefore, researchers are interested in finding a way to …