Physical activity can treat and prevent depressive symptoms, but its antidepressant
mechanisms are yet to be established. In this review, we comprehensively assess key …

Loneliness is associated with increased morbidity and mortality. Deeper understanding of
neurobiological mechanisms underlying loneliness is needed to identify potential …

Although women experience significantly higher tau burden and increased risk for
Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …

Background Neuroimaging studies have shown structural alterations in several brain
regions in children and adults with attention deficit hyperactivity disorder (ADHD). Through …

An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …

Recent work continues to place cholinergic circuits at center stage for normal executive and
mnemonic functioning and provides compelling evidence that the loss of cholinergic …

The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …

We report the development of a 3D OrbiSIMS instrument for label-free biomedical imaging. It
combines the high spatial resolution of secondary ion mass spectrometry (SIMS; under 200 …

We describe an integrative model that encodes associations between related concepts in
the human hippocampal formation, constituting the skeleton of episodic memories. The …

Importance The association between poverty and unfavorable cognitive outcomes is robust,
but most research has focused on individual household socioeconomic status (SES). There …