Licensed London taxi drivers show that humans have a remarkable capacity to acquire and
use knowledge of a large complex city to navigate within it. Gray matter volume differences …

Orientation is a fundamental mental function that processes the relations between the
behaving self to space (places), time (events), and person (people). Behavioral and …

The concept of a (single) limbic system is shown to be outmoded. Instead, anatomical,
neurophysiological, functional neuroimaging, and neuropsychological evidence is …

Normal aging and mild Alzheimer's disease (AD) are associated with declines in
navigational skills, including allocentric and egocentric representations, cognitive mapping …

The authors model the neural mechanisms underlying spatial cognition, integrating
neuronal systems and behavioral data, and address the relationships between long-term …

Mechanisms governing how immune cells and their derived molecules impact homeostatic
brain function are still poorly understood. Here, we elucidate neuronal mechanisms …

Rats and mice have been demonstrated to show episodic-like memory, a prototype of
episodic memory, as defined by an integrated memory of the experience of an object or …

Sleep benefits memory consolidation. The reviewed studies indicate that this consolidating
effect is not revealed under all circumstances but is linked to specific psychological …

Episodic memory is defined as the ability to recall events in a spatiotemporal context.
Formation of such memories is critically dependent on the hippocampal formation and its …

Forming distinct representations of multiple contexts, places, and episodes is a crucial
function of the hippocampus. The dentate gyrus subregion has been suggested to fulfill this …