Alzheimer's disease (AD) is an age-related neurodegenerative disease with multiple
predisposing factors and complicated pathogenesis. Aβ peptide is one of the most important …

Obesity mediates most of its direct medical sequelae through the development of insulin
resistance (IR). The cellular effects of insulin occur through two main postreceptor pathways …

Alzheimer's disease (AD) is the main type of dementia and is a disease with a profound
socioeconomic burden due to the lack of effective treatment. In addition to genetics and …

There is strong evidence that diabetes mellitus increases the risk of cognitive impairment
and dementia. Insulin signaling dysregulation and small vessel disease in the base of …

Compelling preclinical and clinical evidence supports a pathophysiological connection
between Alzheimer's disease (AD) and diabetes. Altered metabolism, inflammation, and …

Alzheimer's disease (AD) is the most common form of dementia affecting elderly people. AD
is a multifaceted pathology characterized by accumulation of extracellular neuritic plaques …

Alzheimer's disease (AD) is the 3rd most costly disease and the leading cause of dementia.
It can linger for many years, but ultimately is fatal, the 6th leading cause of death …

Alzheimer's disease (AD) is the most common cause of dementia and one of the most
important causes of morbidity and mortality among the aging population. AD diagnosis is …

Alzheimer's disease (AD) is a highly complex neurodegenerative disorder of the aged that
has multiple factors which contribute to its etiology in terms of initiation and progression. This …

Melatonin, a pineal gland synthesized neurohormone is known as a multifunctioning
pleiotropic agent which has a wide range of neuroprotective role in manifold age-related …