The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets
A Adamu, S Li, F Gao, G Xue - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Neuroinflammation refers to a highly complicated reaction of the central nervous system
(CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a …
(CNS) to certain stimuli such as trauma, infection, and neurodegenerative diseases. This is a …
[HTML][HTML] Alzheimer's Amyloid Hypothesis and Antibody Therapy: Melting Glaciers?
The amyloid cascade hypothesis for Alzheimer's disease is still alive, although heavily
challenged. Effective anti-amyloid immunotherapy would confirm the hypothesis' claim that …
challenged. Effective anti-amyloid immunotherapy would confirm the hypothesis' claim that …
Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review
S Nag, O Mitra, G Tripathi, S Samanta… - Immunity …, 2023 - Wiley Online Library
Background Autoimmune diseases (AD) are severe pathophysiological ailments that are
stimulated by an exaggerated immunogenic response towards self‐antigens, which can …
stimulated by an exaggerated immunogenic response towards self‐antigens, which can …
[HTML][HTML] Indole-Based Compounds in the Development of Anti-Neurodegenerative Agents
E Barresi, E Baglini, V Poggetti, J Castagnoli… - Molecules, 2024 - mdpi.com
Neurodegeneration is a gradual decay process leading to the depletion of neurons in both
the central and peripheral nervous systems, ultimately resulting in cognitive dysfunctions …
the central and peripheral nervous systems, ultimately resulting in cognitive dysfunctions …
Unveiling the promise: Exosomes as game‐changers in anti‐infective therapy
VP Chavda, G Luo, R Bezbaruah, T Kalita… - …, 2024 - Wiley Online Library
Extracellular vesicles (EVs)‐based intercellular communication (through exosomes,
microvesicles, and apoptotic bodies) is conserved across all kingdoms of life. In recent …
microvesicles, and apoptotic bodies) is conserved across all kingdoms of life. In recent …
Curcumin-loaded polymeric nanomaterials as a novel therapeutic strategy for Alzheimer's disease: A comprehensive review
JJ Pei, CP Palanisamy, PM Natarajan… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) stands as a formidable challenge in modern medicine,
characterized by progressive neurodegeneration, cognitive decline, and memory …
characterized by progressive neurodegeneration, cognitive decline, and memory …
[HTML][HTML] Hematopoietic Stem Cells and Their Niche in Bone Marrow
Extensive research has explored the functional correlation between stem cells and
progenitor cells, particularly in blood. Hematopoietic stem cells (HSCs) can self-renew and …
progenitor cells, particularly in blood. Hematopoietic stem cells (HSCs) can self-renew and …
[HTML][HTML] Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions
Abstract Central Nervous System (CNS) disorders represent a profound public health
challenge that affects millions of people around the world. Diseases such as Alzheimer's …
challenge that affects millions of people around the world. Diseases such as Alzheimer's …
[HTML][HTML] Precision Nanomedicine with Bio-Inspired Nanosystems: Recent Trends and Challenges in Mesenchymal Stem Cells Membrane-Coated Bioengineered …
In the recent past, the formulation and development of nanocarriers has been elaborated
into the broader fields and opened various avenues in their preclinical and clinical …
into the broader fields and opened various avenues in their preclinical and clinical …
[HTML][HTML] Neuroimmunomodulatory Properties of Laquinimod
Abstract Laquinimod (ABR-215062) is a quinolone-3-carboxamide derivative, which is an
orally active immunostimulatory drug molecule and is being developed for multiple sclerosis …
orally active immunostimulatory drug molecule and is being developed for multiple sclerosis …