Alzheimer's disease (AD) is the most common form of dementia. AD brain pathology starts
decades before the onset of clinical symptoms. One early pathological hallmark is blood …

To match the metabolic demands of the brain, mechanisms have evolved to couple neuronal
activity to vasodilation, thus increasing local cerebral blood flow and delivery of oxygen and …

From the first described AD case in 1901 to the current year 2022, understanding the
pathogenesis of Alzheimer's disease (AD) and dementia has undergone a long and tortuous …

Neurovascular coupling is a critical brain mechanism whereby changes to blood flow
accompany localised neural activity. The breakdown of neurovascular coupling is linked to …

Oxidative stress and neuroinflammation are the main physiopathological changes involved
in the initiation and progression of various neurodegenerative disorders or brain injuries …

Primary open-angle glaucoma (POAG) has been suggested to be a neurodegenerative
disease associated with altered cerebral vascular hemodynamics and widespread …

The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

Vascular dementia (VD) is the second leading cause of dementia after Alzheimer's disease
(AD). The decrease of cerebral blood flow (CBF) to different degrees is one of the main …

The role of cellular changes in the neurovascular unit is increasingly being investigated to
understand the pathogenesis of Alzheimer's disease (AD). The aim of the current study was …

Impaired cerebrovascular function is an early biomarker for cerebral amyloid angiopathy
(CAA), a neurovascular disease characterized by amyloid-β accumulation in the cerebral …