Obesity associated pancreatic ductal adenocarcinoma: Therapeutic challenges
S Mundla, R Malla, MP Adem, JB Foote… - Seminars in Cancer …, 2023 - Elsevier
Obesity is a prominent health issue worldwide and directly impacts pancreatic health, with
obese individuals exhibiting a significant risk for increasing pancreatic ductal …
obese individuals exhibiting a significant risk for increasing pancreatic ductal …
Intercellular crosstalk between cancer cells and cancer-associated fibroblasts via exosomes in gastrointestinal tumors
L Cao, H Ouyang - Frontiers in Oncology, 2024 - frontiersin.org
Gastrointestinal (GI) tumors are a significant global health threat, with high rates of morbidity
and mortality. Exosomes contain various biologically active molecules like nucleic acids …
and mortality. Exosomes contain various biologically active molecules like nucleic acids …
Fateful fat: intra-pancreatic lipids cause pancreatic cancer
MS Petrov - Cell Reports Medicine, 2024 - cell.com
In a Mendelian randomization and prospective cohort study, 1 intra-pancreatic fat increases
the risk of pancreatic cancer. This provides persuasive human evidence of causal relation …
the risk of pancreatic cancer. This provides persuasive human evidence of causal relation …
Emerging mechanisms and promising approaches in pancreatic cancer metabolism
H Wu, M Fu, M Wu, Z Cao, Q Zhang, Z Liu - Cell Death & Disease, 2024 - nature.com
Pancreatic cancer is an aggressive cancer with a poor prognosis. Metabolic abnormalities
are one of the hallmarks of pancreatic cancer, and pancreatic cancer cells can adapt to …
are one of the hallmarks of pancreatic cancer, and pancreatic cancer cells can adapt to …
E3 ubiquitin ligase FBXW11 as a novel inflammatory biomarker is associated with immune infiltration and NF-κB pathway activation in pancreatitis and pancreatic …
P Tan, S Cai, Z Huang, M Li, S Liu, J Chen, W Fu… - Cellular …, 2024 - Elsevier
Background Pancreatic cancer (pancreatic ductal adenocarcinoma, PDAC) is an aggressive
disease with an overall poor prognosis. Pancreatitis is a major risk factor for the …
disease with an overall poor prognosis. Pancreatitis is a major risk factor for the …
A Novel Perspective on Genes Driving Metastatic Pancreatic Cancer Revealed by Single-cell RNA Sequencing
Background: Pancreatic ductal adenocarcinoma (PDAC) is formidable in its advanced,
metastatic stage. Aggressive spread of malignant cells from the pancreas to distant organs …
metastatic stage. Aggressive spread of malignant cells from the pancreas to distant organs …
[PDF][PDF] Explore the relationship between excess body weight and the development of pancreatitis, including the mechanisms through which excess adipose tissue may …
WAS Kazmi, S Khalid, F Sabir - J Ayub Med Coll Abbottabad, 2023 - researchgate.net
Background: Pancreatitis is a debilitating inflammatory condition of the pancreas that has
been associated with various risk factors, including excess body weight. However, the …
been associated with various risk factors, including excess body weight. However, the …