Significance: Iron and oxygen are intimately linked: iron is an essential nutrient utilized as a
cofactor in enzymes for oxygen transport, oxidative phosphorylation, and metabolite …

Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

Microplastics (MPs) have become a global environmental concern. Recent studies have
shown that MPs, of which the predominant type is often polystyrene (PS; known as PS-MPs) …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

It is generally acknowledged that reactive oxygen species (ROS) play crucial roles in a
variety of natural processes in cells. If increased to levels which cannot be neutralized by the …

Abstract Nrf2: INrf2 (Keap1) are cellular sensors of oxidative and electrophilic stress. Nrf2 is
a nuclear factor that controls the expression and coordinated induction of a battery of genes …

Diabetes prevalence is increasing worldwide, especially through the increase of type 2
diabetes. Diabetic nephropathy occurs in up to 40% of diabetic patients and is the leading …

Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

Background and aims Non-alcoholic steatohepatitis (NASH), the potentially progressive
form of nonalcoholic fatty liver disease (NAFLD), is the pandemic liver disease of our time …

Ulcers are a lower-extremity complication of diabetes with high recurrence rates. Oxidative
stress has been identified as a key factor in impaired diabetic wound healing …