Class 1 integrons as invasive species

MR Gillings - Current opinion in microbiology, 2017 - Elsevier
Highlights•Clinical class 1 integrons are descended from a single, recent ancestor.•They
have rapidly spread between diverse bacteria, vertebrate hosts and countries.•This spread …

Integrons in the development of antimicrobial resistance: critical review and perspectives

BA Bhat, RA Mir, H Qadri, R Dhiman… - Frontiers in …, 2023 - frontiersin.org
Antibiotic resistance development and pathogen cross-dissemination are both considered
essential risks to human health on a worldwide scale. Antimicrobial resistance genes …

Xenogenetic evolutionary of integrons promotes the environmental pollution of antibiotic resistance genes—Challenges, progress and prospects

R An, Y Qi, XX Zhang, L Ma - Water Research, 2023 - Elsevier
Environmental pollution of antibiotic resistance genes (ARGs) has been a great public
concern. Integrons, as mobile genetic elements, with versatile gene acquisition systems …

The natural history of integrons

TM Ghaly, MR Gillings, A Penesyan, Q Qi, V Rajabal… - Microorganisms, 2021 - mdpi.com
Integrons were first identified because of their central role in assembling and disseminating
antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically …

Antimicrobial resistance in Romania: updates on gram-negative ESCAPE pathogens in the clinical, veterinary, and aquatic sectors

IC Barbu, I Gheorghe-Barbu, GA Grigore… - International Journal of …, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacteria such as Acinetobacter baumannii,
Pseudomonas aeruginosa, and members of the Enterobacterales order are a challenging …

[HTML][HTML] Integron and its role in antimicrobial resistance: A literature review on some bacterial pathogens

P Sabbagh, M Rajabnia, A Maali… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
In recent years, different acquired resistance mechanisms, including transposons,
bacteriophages, plasmids, and integrons have been identified as involved in the spread of …

Conserved phylogenetic distribution and limited antibiotic resistance of class 1 integrons revealed by assessing the bacterial genome and plasmid collection

AN Zhang, LG Li, L Ma, MR Gillings, JM Tiedje… - Microbiome, 2018 - Springer
Background Integrons, especially the class 1 integrons, are major contributors to the
acquisition and dissemination of antibiotic resistance genes (ARGs). However …

The Resistome, Mobilome, Virulome and Phylogenomics of Multidrug-Resistant Escherichia coli Clinical Isolates from Pretoria, South Africa

NM Mbelle, C Feldman, J Osei Sekyere, NE Maningi… - Scientific Reports, 2019 - nature.com
Antibiotic-resistant Escherichia coli is a common occurrence in food, clinical, community and
environmental settings worldwide. The resistome, mobilome, virulome and phylogenomics …

Insights on the Horizontal Gene Transfer of Carbapenemase Determinants in the Opportunistic Pathogen Acinetobacter baumannii

GJ Da Silva, S Domingues - Microorganisms, 2016 - mdpi.com
Horizontal gene transfer (HGT) is a driving force to the evolution of bacteria. The fast
emergence of antimicrobial resistance reflects the ability of genetic adaptation of pathogens …

Multidrug resistance (MDR) and collateral sensitivity in bacteria, with special attention to genetic and evolutionary aspects and to the perspectives of antimicrobial …

A Fodor, BA Abate, P Deák, L Fodor, E Gyenge… - Pathogens, 2020 - mdpi.com
Antibiotic poly-resistance (multidrug-, extreme-, and pan-drug resistance) is controlled by
adaptive evolution. Darwinian and Lamarckian interpretations of resistance evolution are …